中华耳鼻咽喉头颈外科杂志
中華耳鼻嚥喉頭頸外科雜誌
중화이비인후두경외과잡지
CHINESE JOURNAL OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY
2012年
5期
379-382
,共4页
王泽海%林文森%李书彦%赵绍成%王丽%杨仲刚%陈洁%张振富%于金珍
王澤海%林文森%李書彥%趙紹成%王麗%楊仲剛%陳潔%張振富%于金珍
왕택해%림문삼%리서언%조소성%왕려%양중강%진길%장진부%우금진
鼻炎,变应性,常年性%鼻炎,变应性,季节性%哮喘%皮炎,特应性%流行病学因素%患病率%变应原
鼻炎,變應性,常年性%鼻炎,變應性,季節性%哮喘%皮炎,特應性%流行病學因素%患病率%變應原
비염,변응성,상년성%비염,변응성,계절성%효천%피염,특응성%류행병학인소%환병솔%변응원
Rhinitis,allergic,perennial%Rhinitis,allergic,seasonal%Asthma%Dermatitis,atopic%Epidemiologic factors%Prevalence%Allergens
目的 在获取我国北方不同地区变应性鼻炎(allergic rhinitis,AR)患病率的基础上,分析AR患病与哮喘(bronchial asthma,BA)和特应性皮炎(atopic dermatitis,AD)间的相关性及相互影响,为防治AR等变应性疾病提供参考.方法 自2007年4月至2010年5月,通过随机整群和多级抽样,抽取河北省沧州市农村、渤海湾黄骅市沿海渔村、承德市雾灵山区、天津市区内的人群共计1524人,采用面对面直接人户调查并结合血清特异性IgE( specific IgE,slgE)检测结果,获得AR、BA及AD患病与年龄、职业、特应性体质、烟酒嗜好等指标的关系,同时通过相关性的单因素分析和多因素的Logistic回归分析方法,探讨3种变应性疾病间的相关性.结果 我国北方地区AR、BA、AD患病率分别为9.1％、5.4％、6.0％.在AR患者中BA、AD患病率分别为30.9％、29.5％,在无AR人群中BA、AD患病率分别为2.9％、3.7％,差异有统计学意义(x2值分别为192.97、148.40,P值均＜0.01).多因素的Logistic回归分析显示,有BA者患AR的风险是无BA者的8.619倍；有AD患者患AR的风险是无AD者的1.817倍.务工者患AR的风险是务农者的2.320倍.生活居住地变迁患AR仅为无变迁者的0.353倍.结论 AR、BA及AD患病存在相关性,BA与AR的关联强度大于AD与AR的关联强度.
目的 在穫取我國北方不同地區變應性鼻炎(allergic rhinitis,AR)患病率的基礎上,分析AR患病與哮喘(bronchial asthma,BA)和特應性皮炎(atopic dermatitis,AD)間的相關性及相互影響,為防治AR等變應性疾病提供參攷.方法 自2007年4月至2010年5月,通過隨機整群和多級抽樣,抽取河北省滄州市農村、渤海灣黃驊市沿海漁村、承德市霧靈山區、天津市區內的人群共計1524人,採用麵對麵直接人戶調查併結閤血清特異性IgE( specific IgE,slgE)檢測結果,穫得AR、BA及AD患病與年齡、職業、特應性體質、煙酒嗜好等指標的關繫,同時通過相關性的單因素分析和多因素的Logistic迴歸分析方法,探討3種變應性疾病間的相關性.結果 我國北方地區AR、BA、AD患病率分彆為9.1％、5.4％、6.0％.在AR患者中BA、AD患病率分彆為30.9％、29.5％,在無AR人群中BA、AD患病率分彆為2.9％、3.7％,差異有統計學意義(x2值分彆為192.97、148.40,P值均＜0.01).多因素的Logistic迴歸分析顯示,有BA者患AR的風險是無BA者的8.619倍；有AD患者患AR的風險是無AD者的1.817倍.務工者患AR的風險是務農者的2.320倍.生活居住地變遷患AR僅為無變遷者的0.353倍.結論 AR、BA及AD患病存在相關性,BA與AR的關聯彊度大于AD與AR的關聯彊度.
목적 재획취아국북방불동지구변응성비염(allergic rhinitis,AR)환병솔적기출상,분석AR환병여효천(bronchial asthma,BA)화특응성피염(atopic dermatitis,AD)간적상관성급상호영향,위방치AR등변응성질병제공삼고.방법 자2007년4월지2010년5월,통과수궤정군화다급추양,추취하북성창주시농촌、발해만황화시연해어촌、승덕시무령산구、천진시구내적인군공계1524인,채용면대면직접인호조사병결합혈청특이성IgE( specific IgE,slgE)검측결과,획득AR、BA급AD환병여년령、직업、특응성체질、연주기호등지표적관계,동시통과상관성적단인소분석화다인소적Logistic회귀분석방법,탐토3충변응성질병간적상관성.결과 아국북방지구AR、BA、AD환병솔분별위9.1％、5.4％、6.0％.재AR환자중BA、AD환병솔분별위30.9％、29.5％,재무AR인군중BA、AD환병솔분별위2.9％、3.7％,차이유통계학의의(x2치분별위192.97、148.40,P치균＜0.01).다인소적Logistic회귀분석현시,유BA자환AR적풍험시무BA자적8.619배；유AD환자환AR적풍험시무AD자적1.817배.무공자환AR적풍험시무농자적2.320배.생활거주지변천환AR부위무변천자적0.353배.결론 AR、BA급AD환병존재상관성,BA여AR적관련강도대우AD여AR적관련강도.
Objective To obtain the prevalence of allergic rhinitis (AR) in different regions of northern China,to analyze the correlation and interaction between AR and bronchial asthma (BA) or atopic dermatitis ( AD),and to provide reference for the prevention and treatment of allergic diseases such as AR.Methods To obtain the indexes including age,occupation,atopic physical fitness,smoking,alcohol,lifestyle and so on.To explore the correlation between AR and BA or AD.From April 2007 to May 2010,the serum specific IgE(slgE) was investigated in different regions( rural areas of Qingxian,Hebei; coastal fishing village of Bohai Bay,Huanghua; area of Wuling Mountain,Chengde; urban areas of Tianjin ) by randomly multi-stage and cluster sampling,with total population of 1524.Results The prevalence of AR,BA and AD were 9.1％,5.4％ and 6.0％.The prevalence of BA and AD were 30.9％ and 29.5％ in AR patients,but were 2.9％ and 3.7％ in non-AR,and the differences were of statistical significance( x2 values were 192.97 and 148.40,respectively,all P ＜0.01 ).The risk of people with BA suffering from AR was as 8.619 times as those free from BA,the risk of people with AD suffering from AR was as 1.817 times as those free from AD and,the risk of workers suffering from AR was as 2.320 times as farmers in terms of working factor by analysis of Logistic regression for AR and BA,AD,age,occupation,atopic physical fitness and other factors.Conclusions The prevalence of AR are correlated with BA and AD.It is greater between BA and AR than AD and AR in the strength of correlation.
