国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2008年
10期
878-879,882
,共3页
李晨%安云庆%吕哲%马岳珠%董云英%陈惠
李晨%安雲慶%呂哲%馬嶽珠%董雲英%陳惠
리신%안운경%려철%마악주%동운영%진혜
葡萄球菌,金黄色%甲氧西林抗药性%基因%抗药性,细菌
葡萄毬菌,金黃色%甲氧西林抗藥性%基因%抗藥性,細菌
포도구균,금황색%갑양서림항약성%기인%항약성,세균
Staphylococcus aureus%MethiciUin resistance%Genes%Drug resistance,Bac-terial
目的 了解耐甲氧西林金黄色葡萄球菌(MRSA)耐药现状,加强临床MRSA的监控.方法 回顾性分析临床46株MRSA耐药性,并用PCR法对MRSA进行β-内酰胺类耐药相关基因mecA、氨基糖甙类耐药相关基因aac(6')/aph(2")、红霉素类耐药基因emr和耐消毒剂基因qac(A/B)检测.结果 46株MRSA表现多重耐药和高度耐药性,并检测出相关的耐药基因.结论 在临床工作中加强MRSA的监测、合理使用抗生素、严格消毒隔离制度是控制MRSA医院感染的关键.
目的 瞭解耐甲氧西林金黃色葡萄毬菌(MRSA)耐藥現狀,加彊臨床MRSA的鑑控.方法 迴顧性分析臨床46株MRSA耐藥性,併用PCR法對MRSA進行β-內酰胺類耐藥相關基因mecA、氨基糖甙類耐藥相關基因aac(6')/aph(2")、紅黴素類耐藥基因emr和耐消毒劑基因qac(A/B)檢測.結果 46株MRSA錶現多重耐藥和高度耐藥性,併檢測齣相關的耐藥基因.結論 在臨床工作中加彊MRSA的鑑測、閤理使用抗生素、嚴格消毒隔離製度是控製MRSA醫院感染的關鍵.
목적 료해내갑양서림금황색포도구균(MRSA)내약현상,가강림상MRSA적감공.방법 회고성분석림상46주MRSA내약성,병용PCR법대MRSA진행β-내선알류내약상관기인mecA、안기당대류내약상관기인aac(6')/aph(2")、홍매소류내약기인emr화내소독제기인qac(A/B)검측.결과 46주MRSA표현다중내약화고도내약성,병검측출상관적내약기인.결론 재림상공작중가강MRSA적감측、합리사용항생소、엄격소독격리제도시공제MRSA의원감염적관건.
Objective To investigate the drug resistance status of methicillin-resistant Staphylo-coccus aureus (MRSA), strengthen the monitoring of MRSA. Methods Drug resistance of 46 strains of MRSA was retrospectively analyzed. β-lactams resistance gene mecA, aminoglycosides resistance gene sac (6') / aph (2"), erythromyeins resistance gene emr and antiseptics resistance gene qac (A/B) were tested in 46 strains of MRSA by applying PCR. Results Most of MRSA strains were highly and multidrug-resistant, and related resistant genes of MRSA were detected. Conclusion Enhancement of MRSA monitoring, rational use of antibiotics and strict disinfection/insulation in clinic are the key to control of MRSA hospital infection.
