CAJ | 학술논문

PET-CT已成为当今恶性肿瘤诊断、分期及疗效评价必不可少的工具,但是,MRI具有比CT更好的软组织分辨力,还可提供多种生理功能、多序列和多参数成像,且无放射性损伤,其与PET提供的分子信息互补、融合,有望成为新的双模式显像工具,在基础和临床研究中将起着至关重要的作用.然而PET与MRI结合在技术上具有很多挑战,近几年来成为分子影像学研究的热点,并已取得了重大进展.该文对PET-MRI融合技术及设备、初步应用及多模式探针的研究进展等作相关综述.
PET-CT이성위당금악성종류진단、분기급료효평개필불가소적공구,단시,MRI구유비CT경호적연조직분변력,환가제공다충생리공능、다서렬화다삼수성상,차무방사성손상,기여PET제공적분자신식호보、융합,유망성위신적쌍모식현상공구,재기출화림상연구중장기착지관중요적작용.연이PET여MRI결합재기술상구유흔다도전,근궤년래성위분자영상학연구적열점,병이취득료중대진전.해문대PET-MRI융합기술급설비、초보응용급다모식탐침적연구진전등작상관종술.
PET-CT multimodality imaging has become an essential tool for diagnosis,staging and therapeutic evaluation for malignancy.But MRI has better soft tissue resolution than CT,and provides a variety of functional imaging,multi-sequence and multi-parameter imaging,and has no radiation damage.The integration of plentiful information from MRI and molecular information provided by PET is expected to become a new dual-mode imaging tool which will play a very important role in basic and clinical research.However,many challenges are existed in the combined PET and MRI technology,and it has become a focus in molecular imaging research in recent years,and has made significant progress.This paper overviews the progresses of PET-MRI integration technologies and devices,preliminary applications and multimodality probes.