CAJ | 학술논문

[目的]分析老年急性白血病临床特点,化疗方案及预后疗效等.[方法]对2003年至2010年间初治老年急性白血病37例进行分析,中位年龄71岁(60 ～ 93岁),男16例,女21例.急性淋巴细胞白血病(ALL)5例；急性非淋巴细胞白血病(AML)32例,以M2 (40.6％)为主.26例患者接受联合化疗,治疗予NA、TA及NAOP 方案进行联合化疗.[结果]完全缓解率26.9％,2年存活率11.5％,死亡率81％.[结论]老年急性白血病总体缓解率低,死亡率高,化疗耐受性差.
[목적]분석노년급성백혈병림상특점,화료방안급예후료효등.[방법]대2003년지2010년간초치노년급성백혈병37례진행분석,중위년령71세(60 ～ 93세),남16례,녀21례.급성림파세포백혈병(ALL)5례；급성비림파세포백혈병(AML)32례,이M2 (40.6％)위주.26례환자접수연합화료,치료여NA、TA급NAOP 방안진행연합화료.[결과]완전완해솔26.9％,2년존활솔11.5％,사망솔81％.[결론]노년급성백혈병총체완해솔저,사망솔고,화료내수성차.
[Objective]To analyze the clinic characteristics,treatment and prognosis of acute leukemia in elderly patients.[Methods]37 cases of acute leukemia who were older than 60 years from Jan,2003 to Jan,2010 were studied retrospectively.The median age was 71 (ranging from 60 to 93),including 16 male cases and 21 female cases.Among them,5 cases were acute lymphocytic leukemia (ALL) and 32 cases were non-lymphocytic leukemia (ANLL).26patients received chemotherapy such as NA,TA and NAOP.[Results]Complete remission (CR) rate was 26.9％,2 years of survival rate was 11.5％,and mortality was 81％.[Conclusion]The CR rate of acute leukemia in elderly is low and mortality rate is high.Supportive treatment such as infection prevention should be emphasized during chemotherapy.