中国医药
中國醫藥
중국의약
CHINA MEDICINE
2012年
5期
579-581
,共3页
疣状胃炎%内镜%氩离子凝固术
疣狀胃炎%內鏡%氬離子凝固術
우상위염%내경%아리자응고술
Varioliform gastritis%Endoscopy%Argon plasma coagulation
目的 探讨成熟型疣状胃炎的临床特点,分析内镜下治疗的效果.方法 比较成熟型疣状胃炎(134例)、未成熟型疣状胃炎(435例)及非疣状糜烂性胃炎(673例)的临床表现、病理表现、幽门螺杆菌(Hp)感染率等,分析成熟性疣状胃炎的临床特点.将134例成熟型疣状胃炎患者随机分为氩离子凝固术(APC)组(70例)、药物组(64例),APC组采用内镜进行APC+奥美拉唑口服,药物组给予质子泵抑制剂+硫糖铝口服,比较2组症状总有效率、内镜下疣状病灶消除率及抗Hp有效率.结果 成熟型疣状胃炎上腹痛、腹胀、黑便或潜血阳性等发生率,病理表现中肠上皮化生发生率、上皮内瘤变(不典型增生)发生率均明显高于未成熟型疣状胃炎和非疣状糜烂性胃炎(P＜0.05),Hp感染率差异无统计学意义(P＞0.05).APC组患者中70例经APC治疗4周后,58例(82.9％)患者临床症状消失,治疗7周后复查胃镜,42例(60.0％)原病灶已消失,无瘢痕形成,症状总有效率92.9％,内镜下疣状病灶总消除率100％；药物组64例治疗4周后20例(31.3％)症状消失,7周后复查胃镜仅12例(18.7％)疣状改变消失,症状总有效率79.7％,内镜下疣状病灶总消除率71.8％.APC组抗Hp治疗有效42例,占75.0％；药物组抗Hp治疗有效32例,占71.1％.成熟型疣状胃炎APC组症状总有效率、内镜下疣状病灶消除率优于药物组(P＜0.05),2组抗Hp疗效比较差异无统计学意义(P＞0.05).结论 成熟型疣状胃炎具有较为独特的临床特征,APC结合药物治疗成熟型疣状胃炎是一种安全、有效的方法.
目的 探討成熟型疣狀胃炎的臨床特點,分析內鏡下治療的效果.方法 比較成熟型疣狀胃炎(134例)、未成熟型疣狀胃炎(435例)及非疣狀糜爛性胃炎(673例)的臨床錶現、病理錶現、幽門螺桿菌(Hp)感染率等,分析成熟性疣狀胃炎的臨床特點.將134例成熟型疣狀胃炎患者隨機分為氬離子凝固術(APC)組(70例)、藥物組(64例),APC組採用內鏡進行APC+奧美拉唑口服,藥物組給予質子泵抑製劑+硫糖鋁口服,比較2組癥狀總有效率、內鏡下疣狀病竈消除率及抗Hp有效率.結果 成熟型疣狀胃炎上腹痛、腹脹、黑便或潛血暘性等髮生率,病理錶現中腸上皮化生髮生率、上皮內瘤變(不典型增生)髮生率均明顯高于未成熟型疣狀胃炎和非疣狀糜爛性胃炎(P＜0.05),Hp感染率差異無統計學意義(P＞0.05).APC組患者中70例經APC治療4週後,58例(82.9％)患者臨床癥狀消失,治療7週後複查胃鏡,42例(60.0％)原病竈已消失,無瘢痕形成,癥狀總有效率92.9％,內鏡下疣狀病竈總消除率100％；藥物組64例治療4週後20例(31.3％)癥狀消失,7週後複查胃鏡僅12例(18.7％)疣狀改變消失,癥狀總有效率79.7％,內鏡下疣狀病竈總消除率71.8％.APC組抗Hp治療有效42例,佔75.0％；藥物組抗Hp治療有效32例,佔71.1％.成熟型疣狀胃炎APC組癥狀總有效率、內鏡下疣狀病竈消除率優于藥物組(P＜0.05),2組抗Hp療效比較差異無統計學意義(P＞0.05).結論 成熟型疣狀胃炎具有較為獨特的臨床特徵,APC結閤藥物治療成熟型疣狀胃炎是一種安全、有效的方法.
목적 탐토성숙형우상위염적림상특점,분석내경하치료적효과.방법 비교성숙형우상위염(134례)、미성숙형우상위염(435례)급비우상미란성위염(673례)적림상표현、병리표현、유문라간균(Hp)감염솔등,분석성숙성우상위염적림상특점.장134례성숙형우상위염환자수궤분위아리자응고술(APC)조(70례)、약물조(64례),APC조채용내경진행APC+오미랍서구복,약물조급여질자빙억제제+류당려구복,비교2조증상총유효솔、내경하우상병조소제솔급항Hp유효솔.결과 성숙형우상위염상복통、복창、흑편혹잠혈양성등발생솔,병리표현중장상피화생발생솔、상피내류변(불전형증생)발생솔균명현고우미성숙형우상위염화비우상미란성위염(P＜0.05),Hp감염솔차이무통계학의의(P＞0.05).APC조환자중70례경APC치료4주후,58례(82.9％)환자림상증상소실,치료7주후복사위경,42례(60.0％)원병조이소실,무반흔형성,증상총유효솔92.9％,내경하우상병조총소제솔100％；약물조64례치료4주후20례(31.3％)증상소실,7주후복사위경부12례(18.7％)우상개변소실,증상총유효솔79.7％,내경하우상병조총소제솔71.8％.APC조항Hp치료유효42례,점75.0％；약물조항Hp치료유효32례,점71.1％.성숙형우상위염APC조증상총유효솔、내경하우상병조소제솔우우약물조(P＜0.05),2조항Hp료효비교차이무통계학의의(P＞0.05).결론 성숙형우상위염구유교위독특적림상특정,APC결합약물치료성숙형우상위염시일충안전、유효적방법.
Objective To investigate the clinic characteristics of mature varioliform gastritis,and to analyze the merits of endoscopic treatments compared with flaws.Methods The clinical symptoms,the pathological characteristics and the rate of Helicobacter pylori infection were compared among the cases of mature varioliform gastritis,immature varioliform gastritis and commonerosivegastritis.The 134 cases were arranged into argon plasma coagulation (APC) group and drug group.The cases in APC group were given argon plasma coagulation and the cases in drug group were given drug treatment.Results The occurring rates of abdominal pain,distention,heartburn,hemafecia,intestinal metaplastia and atypical hyperplasia in the pathological results inthe cases of mature varioliform gastritis were higher than those in other cases(P ＜ 0.05 ),but there was not a significant difference of the rate of Helicobacter pylori infection (P ＞ 0.05).No significant differences between two groups regarding anti-Helicobacter pylori effects were observed(P ＞ 0.05).Conclusions As a special erosivegastritis,the cases with mature varioliform gastritis can have particular clinical symptoms.The argon plasma coagulation can be an optimal method to treat the disease.
