CAJ | 학술논문

为研究龙胆草(Gentiana scabra Bunge)地上部分的化学成分,利用硅胶柱色谱对其乙醇提取物进行分离纯化,根据理化性质和波谱方法鉴定了化合物的结构.分离得到β-香树脂醇(1)、β-谷甾醇(2)、β-香树脂醇乙酸酯(3)、乌苏醇(4)、齐墩果酸(5)、6-去甲氧基-7-甲基菌陈色原酮(6).其中化合物6为首次从龙胆科植物中分离得到的具有2-苯氧基色原酮骨架的天然酚类成分,本文对其1D和2D NMR谱的特征及EI质谱主要碎片的可能裂解方式进行了讨论,利用单晶X-射线衍射方法对其晶体结构进行了分析,为该类天然产物的结构表征提供了依据.
위연구룡담초(Gentiana scabra Bunge)지상부분적화학성분,이용규효주색보대기을순제취물진행분리순화,근거이화성질화파보방법감정료화합물적결구.분리득도β-향수지순(1)、β-곡치순(2)、β-향수지순을산지(3)、오소순(4)、제돈과산(5)、6-거갑양기-7-갑기균진색원동(6).기중화합물6위수차종룡담과식물중분리득도적구유2-분양기색원동골가적천연분류성분,본문대기1D화2D NMR보적특정급EI질보주요쇄편적가능렬해방식진행료토론,이용단정X-사선연사방법대기정체결구진행료분석,위해류천연산물적결구표정제공료의거.
To study the chemical constituents of aerial part of Gentiana scabra Bunge, the plant material was extracted with ethanol, and the constituents were separated and purified from the ethanol extraction by silica gel column chromatog-raphy. They were identified asβ-amyrin (1) ,β-sitosterol (2) ,β-amyrin acetate (3) , uvaol (4) , oleanolic acid (5) and 6-demethoxy-7-methylcapillarisn (6), on the basis of physiochemical properties and spectral methods. Among them, com-pound 6 was isolated from Gentianaceae for the first time. Its characterization by 1D and 2D NMR spectra and possible fragmentation pathway in EI-MS were discussed. The structure of compound 6 was confirmed by X-ray crystallographic a-nalysis.