CAJ | 학술논문

目的探讨液基薄层细胞检测系统(LCT)联合阴道镜及阴道镜下宫颈活检对宫颈上皮内瘤变(CIN)的诊断价值.方法回顾性分析7118例LCT筛查结果及其中778例细胞学阳性行阴道镜下活检的病理结果,167例虽细胞学阴性,但临床高度可疑,行阴道镜检出并取活检.结果 7118例患者中,778例LCT检查提示不典型鳞状细胞以上病变者,再行阴道镜下活检发现CIN以上病变429例,检出率为6.03%(429/7118).167例LCT检查阴性但临床高度可疑病例,行镜下活检CIN以上病变78例,总检出率为7.12%[(429+78)/7118].两者比较差异显著(P<0.01).结论采用LCT筛查可早期发现宫颈病变,细胞学阳性或临床可疑者应配合阴道镜检查及镜下活检可提高CIN的检出率,但如果同时进行阴道镜检查可提高CIN的检出率.
목적 탐토액기박층세포검측계통(LCT)연합음도경급음도경하궁경활검대궁경상피내류변(CIN)적진단개치.방법 회고성분석7118례LCT사사결과급기중778례세포학양성행음도경하활검적병리결과,167례수세포학음성,단림상고도가의,행음도경검출병취활검.결과 7118례환자중,778례LCT검사제시불전형린상세포이상병변자,재행음도경하활검발현CIN이상병변429례,검출솔위6.03%(429/7118).167례LCT검사음성단림상고도가의병례,행경하활검CIN이상병변78례,총검출솔위7.12%[(429+78)/7118].량자비교차이현저(P<0.01).결론 채용LCT사사가조기발현궁경병변,세포학양성혹림상가의자응배합음도경검사급경하활검가제고CIN적검출솔,단여과동시진행음도경검사가제고CIN적검출솔.
Objective To study the diagnostic value of liquid-based thin-layer cell detction system(LCT)and cervical biopsy vagionscopy for cervical intraepithelial neoplasia(CIN).Method The clinical information of 7118 patients that received LCT and 778 cases of positive cytological result that received cervical biopsy were retrospectively analyzed.167 patients with negative result in cytological test received cervical biopsies vaginoscopy because of their high-grade clinical suspicion.Results In 7118 patients,429 cases was diagnosed as CIN by cervical biopsy,the diagnosis rate was 6.03%(429/7118).In 167 patients,78 cases of 778 cases that were suggested as untypical squamous cell lesions by LCT were diagnosed as CIN by cervical biopsy.The total diagnosis rate is 7.12%[(429+78)/7118].There was a significant difference between them(P<0.01).Conclusions LCT could detect cervical lesion in its early stage.The patients whose cytological test results are positive or clinical high-grade suspicious should receive cervical biopsy vaginoscopy,which may benefit to the increase of detection rate of CIN.