CAJ | 학술논문

目的探讨莱姆病心肌损伤流行病学特点.方法采用间接免疫荧光抗体试验(IFA)初步筛查湘南莽山林区莱姆病血清抗体阳性患者,进行莱姆病心肌损伤的诊断和流行病学调查.结果 1 120名林区居民中,莱姆病患者72例,患病率为6.4%,男女莱姆病患病率分别为6.2%和6.7%,男女患病率间差异无统计学意义(P＞0.05).不同年龄组居民莱姆病的感染率比较,差异有统计学意义(P＜0.01).莱姆病心肌损伤患者14例,发生率为19.4%,其中男女心肌损伤比为3∶1.各年龄组莱姆病患者心肌损伤发生率比较,差异无统计学意义(P＞0.05).心肌损伤出现于红斑后21 d(中位数),以房室传导阻滞常见.结论莱姆病患者心肌损伤发生于早期,心肌损伤有性别差异,损伤类型以传导系统功能障碍为主.
목적 탐토래모병심기손상류행병학특점.방법 채용간접면역형광항체시험(IFA)초보사사상남망산림구래모병혈청항체양성환자,진행래모병심기손상적진단화류행병학조사.결과 1 120명림구거민중,래모병환자72례,환병솔위6.4%,남녀래모병환병솔분별위6.2%화6.7%,남녀환병솔간차이무통계학의의(P＞0.05).불동년령조거민래모병적감염솔비교,차이유통계학의의(P＜0.01).래모병심기손상환자14례,발생솔위19.4%,기중남녀심기손상비위3∶1.각년령조래모병환자심기손상발생솔비교,차이무통계학의의(P＞0.05).심기손상출현우홍반후21 d(중위수),이방실전도조체상견.결론 래모병환자심기손상발생우조기,심기손상유성별차이,손상류형이전도계통공능장애위주.
Objective To explore epidemiologic characteristics of Lyme cardiac complications.Methods Indirect immunofluorescence antibody (IFA) was used to screen Lyme myocardial injury patients in Hunan Mangshan Forest Region,to perform its diagnoses and epidemiological investigation.Results In 1120 residents of the forest region,there were 72 patients with Lyme diseases,accounting for 6.4%.There was not significant difference in prevalence of Lyme disease between males and females (6.2%,6.7%,respectively,P＞0.05).There was significant difference in Lyme infection between different age groups (P＜0.01).Lyme myocardiac injury was noted in 14 patients,accounting for 19.4%,the ratio of males to females was 3:1.No significant difference was noted in myocardiac injury incidence between all age groups (P＞0.05).Myocardiac injury appeared on days 21 (median) after erythema,most commonly with atrioventricular block.Conclusion Myocardiac injury occurs at early stage of Lyme disease,with gender difference.The injury type is mainly conduction system dysfunction.