中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2012年
29期
15-17
,共3页
乳腺肿瘤%骨转移%骨型碱性磷酸酶
乳腺腫瘤%骨轉移%骨型堿性燐痠酶
유선종류%골전이%골형감성린산매
Breast neoplasms%Bone metastases%Bone alkaline phosphatase
目的 研究骨型碱性磷酸酶(AKP-3)在乳腺癌术后骨转移中的诊断应用价值.方法 选取50例乳腺癌术后骨转移患者为研究对象,分析血清AKP-3浓度与骨转移的关系,研究其在乳腺癌术后骨转移显像诊断中的应用.结果 50例患者全身骨显像检查分度M09例(18.0%),M114例(28.0%),M2 20例(40.0%),M37例(14.0%),各构成比比较差异无统计学意义(P>0.05).Mo、M1、M2、M3患者血清AKP-3浓度分别为(20.3±6.1)、(42.4±7.4)、(54.1±8.9)、(86.8±9.2) U/L,差异有统计学意义(P<0.05).结论 AKP-3浓度的检测以及动态观察有助于乳腺癌术后骨转移的早期诊断和预后评判.
目的 研究骨型堿性燐痠酶(AKP-3)在乳腺癌術後骨轉移中的診斷應用價值.方法 選取50例乳腺癌術後骨轉移患者為研究對象,分析血清AKP-3濃度與骨轉移的關繫,研究其在乳腺癌術後骨轉移顯像診斷中的應用.結果 50例患者全身骨顯像檢查分度M09例(18.0%),M114例(28.0%),M2 20例(40.0%),M37例(14.0%),各構成比比較差異無統計學意義(P>0.05).Mo、M1、M2、M3患者血清AKP-3濃度分彆為(20.3±6.1)、(42.4±7.4)、(54.1±8.9)、(86.8±9.2) U/L,差異有統計學意義(P<0.05).結論 AKP-3濃度的檢測以及動態觀察有助于乳腺癌術後骨轉移的早期診斷和預後評判.
목적 연구골형감성린산매(AKP-3)재유선암술후골전이중적진단응용개치.방법 선취50례유선암술후골전이환자위연구대상,분석혈청AKP-3농도여골전이적관계,연구기재유선암술후골전이현상진단중적응용.결과 50례환자전신골현상검사분도M09례(18.0%),M114례(28.0%),M2 20례(40.0%),M37례(14.0%),각구성비비교차이무통계학의의(P>0.05).Mo、M1、M2、M3환자혈청AKP-3농도분별위(20.3±6.1)、(42.4±7.4)、(54.1±8.9)、(86.8±9.2) U/L,차이유통계학의의(P<0.05).결론 AKP-3농도적검측이급동태관찰유조우유선암술후골전이적조기진단화예후평판.
Objective To study the diagnostic application value of bone alkaline phosphates (AKP-3) in breast cancer postoperative bone metastases.Methods Fifty cases with breast cancer postoperative bone metastases were selected.The relationship between the serum levels of AKP-3 and bone metastases was analyzed,and the diagnostic application value of AKP-3 in breast cancer postoperative bone metastases was studied.Results According to the degree of the bone imaging,among 50 cases,9 cases in the degree M0,the constituent ratio was 18.0%(9/50); 14 cases in the degree M1,the constituent ratio was 28.0%( 14/50); 20 cases in the degree M2,the constituent ratio was 40.0%(20/50); 7 cases in the degree M3,the constituent ratio was 14.0% (7/50); the constituent ratios were not statistically significant (P >0.05 ).The serum levels of AKP-3 in the degree M0,M 1,M2,M3 were (20.3 ± 6.1 ),(42.4 ± 7.4),(54.1 ±8.9),(86.8 ± 9.2) U/L,the differences were statistically significant (P< 0.05).Conclusion The detection and dynamic observations of AKP-3 help in the early diagnosis and prognostic evaluation of breast cancer postoperative bone metastases.