CAJ | 학술논문

目的应用高场强MRI探讨胎儿基底核区的发育规律.方法选取131例14～40孕周胎儿标本,先行3.0 T MR扫描,从中选取11例14～27孕周标本再行7.0 T MR扫描.在上述MR图像上分析基底核区各结构的出现时间及信号变化.结果在3.0 T MR图像上,14孕周时基底核区仅背侧丘脑能够辨别,15孕周时能辨识生发基质、尾状核与壳,18孕周时能显示苍白球,20孕周时内囊与外囊显示清晰.尾状核在15～30孕周时与脑白质的信号强度相比,在T1WI上呈低信号,T2WI上呈高信号,31～40孕周,在T1WI聊上呈高信号,T2WI上呈低信号.壳在15～17孕周时,在T1WI上呈高信号,T2WI上呈低信号,18～25孕周呈现斑块状外观,26～30孕周在T1WI上呈低信号,T2WI上呈高信号,31～40孕周在T1WI上呈高信号,T2WI上呈低信号.苍白球20孕周后T1WI上呈高信号,T2WI上呈低信号.与3.0 TMRI相比,7.0TT2WI更加清晰,16孕周时生发基质、尾状核、豆状核、背侧丘脑、内囊与外囊均显示清晰,18孕周时能辨别出屏状核.结论 3.0 T MR/可以较好地显示发育中的胎儿基底核区的结构.在14～21孕周,7.O T T2WI比3.0 T MR图像更好地显示胎儿基底核区的结构.
목적 응용고장강MRI탐토태인기저핵구적발육규률.방법 선취131례14～40잉 주태인표본,선행3.0 T MR소묘,종중선취11례14～27잉주표본재행7.0 T MR소묘.재상술MR도상상분석기저핵구각결구적출현시간급신호변화.결과 재3.0 T MR도상상,14잉주시기저핵구부배측구뇌능구변별,15잉주시능변식생발기질、미상핵여각,18잉주시능현시창백구,20잉주시내낭여외낭현시청석.미상핵재15～30잉주시여뇌백질적신호강도상비,재T1WI상정저신호,T2WI상정고신호,31～40잉주,재T1WI료상정고신호,T2WI상정저신호.각재15～17잉주시,재T1WI상정고신호,T2WI상정저신호,18～25잉주정현반괴상외관,26～30잉주재T1WI상정저신호,T2WI상정고신호,31～40잉주재T1WI상정고신호,T2WI상정저신호.창백구20잉주후T1WI상정고신호,T2WI상정저신호.여3.0 TMRI상비,7.0TT2WI경가청석,16잉주시생발기질、미상핵、두상핵、배측구뇌、내낭여외낭균현시청석,18잉주시능변별출병상핵.결론 3.0 T MR/가이교호지현시발육중적태인기저핵구적결구.재14～21잉주,7.O T T2WI비3.0 T MR도상경호지현시태인기저핵구적결구.
Objective To study the developmental process of the region of basal nuclei of postmortem fetuses by 3.0 T and 7.0 T MRI.Methods One hundred and thirty-one postmortem fetuses of 14 to 40 weeks of gestational age(GA)were scanned by 3.0 T MR,of which 11 fetuses of 14-27 weeks of GA were chosen and scanned by 7.0 T MR. The time when the structures in the region of basal nuclei could be detected and the changes of MR signal intensity were analyzed for MRI of different Tesla.Results On 3.0 T MRI.the dorsal thalamus could be delineated as early as 14 weeks of GA. The germinal matrix, caudate nucleus,and putamen could be visualized as early as 15 weeks of GA. The globus pallidus could be described as early as 18 weeks of GA.and the internal capsule and external capsule could be shown as early as 20 weeks of GA. The signal of the caudate nucleus during 15-30 weeks of GA was relatively hypointense on T1WI and hyperintense on T2WI.but during 31-40 weeks of GA, it was relatively hyperintense on T1WI and hypointense on T2WI. The putamen had a relatively high signal intensity on T1WI and low signal intemity on T1WI during 15-17 weeks of GA, and it appeared patchy during 18-25 weeks of GA,then it had a relatively low signal intensity on T1WI and high signal intensity on T2WI during 26-30 weeks of GA, and during 31-40 weeks of GA,its signal intensity was relatively high on T1WI and low on T2WI.The globus pallidus had a relatively high signal intensity on T1WI and low signal intensity on T2WI during 20-40 weeks of GA Compared to the 3.0 T MRI,the T2 images of 7.0 T MRl were more clear,and most structures in the region of basal nuclei could be clearly displayed as early as 16 weeks of GA.such as the germinal matrix,caudate nucleus,dorsal thalamus,putamen,globus pallidus,internal capsule,and external capsule.The claustrum could be delineated as early as 18 weeks of GA on 7.0 T MRI. Conclusions 3.0 T MRI could show the developmental process of the region of basal nuclei well,but the T2 images of 7.0 TMRl were comparatively better.