CAJ | 학술논문

目的探讨Livin、Caspase-3在结肠癌和结肠腺瘤组织中的表达及意义.方法应用免疫组织化学染色方法对50例结肠癌和结肠正常黏膜、50例结肠腺瘤进行Livin、Caspase-3检测.结果结肠癌组织中Livin阳性率明显高于结肠腺瘤和结肠正常黏膜组织(P<0.05).结肠癌组织中Caspase-3阳性率明显低于结肠腺瘤和结肠正常黏膜组织(P<0.05).结腺瘤和结肠正常黏膜组织Livin、Caspase-3阳性率无显著性差异(P>0.05).结论 Livin、Caspase-3在结肠癌中的发生及发展中有一定作用
목적 탐토Livin、Caspase-3재결장암화결장선류조직중적표체급의의.방법 응용면역조직화학염색방법대50례결장암화결장정상점막、50례결장선류진행Livin、Caspase-3검측.결과 결장암조직중Livin양성솔명현고우결장선류화결장정상점막조직(P<0.05).결장암조직중Caspase-3양성솔명현저우결장선류화결장정상점막조직(P<0.05).결선류화결장정상점막조직Livin、Caspase-3양성솔무현저성차이(P>0.05).결론 Livin、Caspase-3재결장암중적발생급발전중유일정작용
Objective To explore the expression and significance of Livin、Caspase-3 protein in the colon carcinoma and colon adenaoma.Methods Immunohistochemistry staining was employed to detect the expression of Livin、Caspase-3 protein in 50 cases of colon carcinoma and 50 cases of colon adenaoma.Results Livin protein positive expression rates in the colon carcinoma tissues were more than those in colon adenaoma tissues.Caspase-3 protein positive expression rates in the colon carcinoma tissues were lower than those in colon adenaoma tissues.There were no marked significances relating to Livin caspases-3 protein positive expression rates in colon adenaoma tissues and normal tissues.Conclusion Livin、caspases-3 play an important role in incidence and development of colon carcinoma