中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
2期
21-24
,共4页
胃肿瘤%淋巴结%肿瘤转移%预后
胃腫瘤%淋巴結%腫瘤轉移%預後
위종류%림파결%종류전이%예후
Stomach neoplasms%Lymph nodes%Neoplasm metastasis%Prognosis
目的 探讨早期胃癌(EGC)淋巴结转移与临床病理特征的关系,找出影响预后因素.方法 回顾性分析1999年7月至2009年6月行胃癌根治术338例EGC患者的临床资料,分析淋巴结转移与肿瘤大小、组织学类型、浸润深度之间的关系;应用Kaplan-Meier法对随访患者资料进行影响预后因素及生存率分析.结果 淋巴结转移与肿瘤大小、浸润深度有关,差异有统计学意义(P<0.05或<0.01).63例随访患者5年生存率为92.1%;肿瘤浸润黏膜层患者5年生存率为97.1%,肿瘤浸润黏膜下层患者5年生存率为85.7%;肿瘤浸润深度、肿瘤大小与EGC术后生存率相关(P值分别为0.043、0.004).结论 根据肿瘤大小、浸润深度、淋巴结转移等生物学特点,合理选择手术方案,有助于提高EGC患者的5年生存率,改善预后.
目的 探討早期胃癌(EGC)淋巴結轉移與臨床病理特徵的關繫,找齣影響預後因素.方法 迴顧性分析1999年7月至2009年6月行胃癌根治術338例EGC患者的臨床資料,分析淋巴結轉移與腫瘤大小、組織學類型、浸潤深度之間的關繫;應用Kaplan-Meier法對隨訪患者資料進行影響預後因素及生存率分析.結果 淋巴結轉移與腫瘤大小、浸潤深度有關,差異有統計學意義(P<0.05或<0.01).63例隨訪患者5年生存率為92.1%;腫瘤浸潤黏膜層患者5年生存率為97.1%,腫瘤浸潤黏膜下層患者5年生存率為85.7%;腫瘤浸潤深度、腫瘤大小與EGC術後生存率相關(P值分彆為0.043、0.004).結論 根據腫瘤大小、浸潤深度、淋巴結轉移等生物學特點,閤理選擇手術方案,有助于提高EGC患者的5年生存率,改善預後.
목적 탐토조기위암(EGC)림파결전이여림상병리특정적관계,조출영향예후인소.방법 회고성분석1999년7월지2009년6월행위암근치술338례EGC환자적림상자료,분석림파결전이여종류대소、조직학류형、침윤심도지간적관계;응용Kaplan-Meier법대수방환자자료진행영향예후인소급생존솔분석.결과 림파결전이여종류대소、침윤심도유관,차이유통계학의의(P<0.05혹<0.01).63례수방환자5년생존솔위92.1%;종류침윤점막층환자5년생존솔위97.1%,종류침윤점막하층환자5년생존솔위85.7%;종류침윤심도、종류대소여EGC술후생존솔상관(P치분별위0.043、0.004).결론 근거종류대소、침윤심도、림파결전이등생물학특점,합리선택수술방안,유조우제고EGC환자적5년생존솔,개선예후.
Objective To find out the relationship between lymph node metastasis and clinical pathological specificity, the prognostic factors for the purpose of improving survival of early gastric cancer (EGC) and quality of life. Methods The clinical data of the 338 EGC patients from July 1999 to June 2009 was analyzed retrospectively, includirg the possible relationship of lymph node metastasis, the size of tumor,types of histopathology,depth of infiltration. Using Kaplan-Meier method to process suvival rate,immunohistochemistry method to detect the micrometastasis. Results Lymphnode metastasis was relative to the size of tumor, depth of infiltration (P < 0.05 or < 0.01). Total 5-year survival rate was 92.1%, intramucosa 5-year survival rate 97.1%, submucosa 5-year survival rate was 85.7% in 63 followed up patients, the survival rate of EGC was related with depth of infiltration and size of tumor (P = 0.043,0.004). Conclusion By precisely estimating depth of infiltration, the size of tumor and correct estimating the state of lymph node metastasis, choosing right 5-year surgical protocol can improve EGC survival rate and prognosis.
