CAJ | 학술논문

目的了解浙江省农村人群与主要家畜蜱媒传染病病原体感染的情况.方法按地理位置和蜱媒传染病病原体历史检测情况,选择浙西北丘陵区的安吉县、浙中丘陵盆地区的金东区和浙东盆地低山区的天台县为调查点,采集3个调查点农村人群和家畜血标本,以间接免疫荧光法检测黑龙江立克次体、恙虫病东方体、莫氏立克次体、嗜吞噬无形体、查菲埃立克体、巴尔通体、海南立克次体和贝纳柯克斯体8种常见蜱媒传染病病原体IgG抗体.结果 3个调查点共检测683份血清标本,包括579份人标本和104份家畜标本(牛53份、羊51份),不同地区恙虫病东方体、莫氏立克次体、查菲埃立克体、贝纳柯克斯体4种病原体抗体阳性率差异有统计学意义(P值均等于0.000).人血清标本8种病原体IgG抗体均检出,阳性率最高的分别是莫氏立克次体(20.7%)、巴尔通体(10.9%)和贝纳柯克斯体(5.5%),其中莫氏立克次体抗体阳性率随年龄增长而增加.家畜血清标本除嗜吞噬无形体外其余7种病原体IgG抗体均检出,阳性率最高的是莫氏立克次体(69.2%)、巴尔通体(51.0%)和海南立克次体(22.1%),不同家畜抗体阳性情况不同.结论浙江省不同地区农村人群与家畜中广泛存在多种蜱媒传染病病原体的感染,特别是莫氏立克次体、巴尔通体、海南立克次体和贝纳柯克斯体抗体阳性率较高.
목적 료해절강성농촌인군여주요가축비매전염병병원체감염적정황.방법 안지리위치화비매전염병병원체역사검측정황,선택절서북구릉구적안길현、절중구릉분지구적금동구화절동분지저산구적천태현위조사점,채집3개조사점농촌인군화가축혈표본,이간접면역형광법검측흑룡강립극차체、양충병동방체、막씨립극차체、기탄서무형체、사비애립극체、파이통체、해남립극차체화패납가극사체8충상견비매전염병병원체IgG항체.결과 3개조사점공검측683빈혈청표본,포괄579빈인표본화104빈가축표본(우53빈、양51빈),불동지구양충병동방체、막씨립극차체、사비애립극체、패납가극사체4충병원체항체양성솔차이유통계학의의(P치균등우0.000).인혈청표본8충병원체IgG항체균검출,양성솔최고적분별시막씨립극차체(20.7%)、파이통체(10.9%)화패납가극사체(5.5%),기중막씨립극차체항체양성솔수년령증장이증가.가축혈청표본제기탄서무형체외기여7충병원체IgG항체균검출,양성솔최고적시막씨립극차체(69.2%)、파이통체(51.0%)화해남립극차체(22.1%),불동가축항체양성정황불동.결론 절강성불동지구농촌인군여가축중엄범존재다충비매전염병병원체적감염,특별시막씨립극차체、파이통체、해남립극차체화패납가극사체항체양성솔교고.
Objective To investigate the seroprevalence of tick-borne diseases in humans and domestic animals from rural areas of Zhejiang province. Methods Anji county, Jindong district and Tiantai county were selected for samples collection according to their geographic locations and historical prevalence of tick-borne diseases. Blood samples of humans and domestic animals were collected in the three sites. An indirect immuno-fluorescent antibody test was used to determine the presence of IgG antibodies of Rickettsiae heilongjiangii, Orientia tsutsugamushi, R. typhi, Anaplasma phagocytos, Ehrlichia chaffeensis, Bartonella, R. hainan and Coxiella burnetii in these samples.Results Six hundred and eighty-three blood samples including 579 from humans and 104 from domestic animals(53 from cattles and 51 from sheep)were collected from the three sites. Antibody positive rates of Orientia tsutsugamushi, R. typhi, Ehrlichia chaffeensis and Coxiella burnetii were significantly different between these sites. IgG from all the 8 pathogens were detected in samples from humans. It was found that the sero-prevalence rates of R. typhi, Bartonella and C. burnetii(20.7%,10.9%, 5.5%)of adults were higher than those of other Rickettsiae under investigation. The seroprevalence of R. typhi increased along with age. IgG from the 7 pathogens were detected in samples from domestic animals except for Anaplasma phagocytos. The sero-prevalence rates of R. typhi, Bartonella and R. hainan(69.2%, 51.0%, 22.1%)of adults were higher than those of other Rickettsiae investigated. Conclusion Tick-borne diseases did spread widely in humans and domestic animals from different rural areas of Zhejiang province. The sero-prevalence rates of R. typhi,B. henselae, R. hainan and C. burnetii were higher than that from other pathogens.