国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2011年
7期
490-492
,共3页
慢性阻塞性肺疾病%噻托溴铵%沙美特罗/丙酸氟替卡松%肺功能
慢性阻塞性肺疾病%噻託溴銨%沙美特囉/丙痠氟替卡鬆%肺功能
만성조새성폐질병%새탁추안%사미특라/병산불체잡송%폐공능
Chronic obstructive pulmonary disease%Tiotropium bromide%Salmeterol/fluticasone propionate%Pulmonary function
目的 观察沙美特罗/丙酸氟替卡松(舒利迭)联合噻托溴铵粉吸入剂(思力华)对慢性阻塞性肺疾病(COPD)缓解期的治疗效果.方法 采用随机、双肓的方法将85例COPD患者分为观察组和对照组,观察组A组给予噻托溴铵和沙美特罗/丙酸氟替卡松治疗,对照组B组给予沙美特罗/内酸氟替卡松治疗.分别对两组患者治疗前后的呼吸困难的评分、肺功能的检测和6分钟步行距离(6MWD)的情况进行比较.结果 治疗3个月后,与对照组比较,观察组肺功能指标FEV1、FEV1/FVC%、生活质量评分及6MWD,差异有统计学意义(P＜0.05).结论 噻托溴铵与沙美特罗/丙酸氟替卡松联合吸入治疗COPD,疗效优于沙美特罗替卡松单药治疗.
目的 觀察沙美特囉/丙痠氟替卡鬆(舒利迭)聯閤噻託溴銨粉吸入劑(思力華)對慢性阻塞性肺疾病(COPD)緩解期的治療效果.方法 採用隨機、雙肓的方法將85例COPD患者分為觀察組和對照組,觀察組A組給予噻託溴銨和沙美特囉/丙痠氟替卡鬆治療,對照組B組給予沙美特囉/內痠氟替卡鬆治療.分彆對兩組患者治療前後的呼吸睏難的評分、肺功能的檢測和6分鐘步行距離(6MWD)的情況進行比較.結果 治療3箇月後,與對照組比較,觀察組肺功能指標FEV1、FEV1/FVC%、生活質量評分及6MWD,差異有統計學意義(P＜0.05).結論 噻託溴銨與沙美特囉/丙痠氟替卡鬆聯閤吸入治療COPD,療效優于沙美特囉替卡鬆單藥治療.
목적 관찰사미특라/병산불체잡송(서리질)연합새탁추안분흡입제(사력화)대만성조새성폐질병(COPD)완해기적치료효과.방법 채용수궤、쌍황적방법장85례COPD환자분위관찰조화대조조,관찰조A조급여새탁추안화사미특라/병산불체잡송치료,대조조B조급여사미특라/내산불체잡송치료.분별대량조환자치료전후적호흡곤난적평분、폐공능적검측화6분종보행거리(6MWD)적정황진행비교.결과 치료3개월후,여대조조비교,관찰조폐공능지표FEV1、FEV1/FVC%、생활질량평분급6MWD,차이유통계학의의(P＜0.05).결론 새탁추안여사미특라/병산불체잡송연합흡입치료COPD,료효우우사미특라체잡송단약치료.
Objective To evaluate the effects of tiotropium bromide combined salmeterol/fluticasone propionate (SFC) for the treatment in patients with stable chronic obstructive pulmonary disease(COPD). Methods A randomized, double blind clinical trial was conducted in 85 patients with stable COPD. Group A was given tiotropium bromide combined with SFC,Group B was given SFC,the St George's respiratory questionnaire (SGRQ), pulmonary function and 6 minute walk distance (6-MWD)was conducted at baseline, 3 monthes after treatment. Results FEV1 , FEV1/FVC%, SGRQ score and 6-MWD in combined group A were significantly superior to those of control group B at 3 monthes after treatment (all P ＜0.05). Conclusions Tiotropium bromide combined SFC could further advance efficacy than SFC for the treatment in patients with stable COPD.
