中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2010年
21期
8-10
,共3页
妇产科,医院%手术期间%抗菌药%对比研究
婦產科,醫院%手術期間%抗菌藥%對比研究
부산과,의원%수술기간%항균약%대비연구
Obstetrics and gynecology department,hospital%Intraoperative period%Anti-bacterial agents%Comparative study
目的 了解发布<关于进一步加强抗菌药物临床应用管理的通知>文件后妇产科围手术期抗菌药物的应用情况.方法 对妇产科2007年4-12月272例手术患者(治疗组)和2008年4-12月270例手术患者(对照组)抗菌药物使用情况进行比较.结果 治疗组和对照组预防性抗菌药物使用率分别为83.09%(226/272)、84.44%(228,270)(P>0.05);术前使用率分别为77.94%(212/272)、85.19%(230/270)(P<0.05);抗菌药物应用时间分别为(5.8±2.8)、(4.5±3.8)d(P<0.01);药敏试验率分别为2.94%(8/272)、2.22%(6/270)(P>0.05);给药途径均以静脉给药为主,且均以二联为主.结论 实施<抗菌药物临床应用指导原则>和<关于进一步加强抗菌药物临床应用管理的通知>后,抗菌药物的应用仍存在用药起点高、手术时间超过3 h无追加、用药时间长且以二联用药为主,存在不足之处需要多方面共同管理和改进.
目的 瞭解髮佈<關于進一步加彊抗菌藥物臨床應用管理的通知>文件後婦產科圍手術期抗菌藥物的應用情況.方法 對婦產科2007年4-12月272例手術患者(治療組)和2008年4-12月270例手術患者(對照組)抗菌藥物使用情況進行比較.結果 治療組和對照組預防性抗菌藥物使用率分彆為83.09%(226/272)、84.44%(228,270)(P>0.05);術前使用率分彆為77.94%(212/272)、85.19%(230/270)(P<0.05);抗菌藥物應用時間分彆為(5.8±2.8)、(4.5±3.8)d(P<0.01);藥敏試驗率分彆為2.94%(8/272)、2.22%(6/270)(P>0.05);給藥途徑均以靜脈給藥為主,且均以二聯為主.結論 實施<抗菌藥物臨床應用指導原則>和<關于進一步加彊抗菌藥物臨床應用管理的通知>後,抗菌藥物的應用仍存在用藥起點高、手術時間超過3 h無追加、用藥時間長且以二聯用藥為主,存在不足之處需要多方麵共同管理和改進.
목적 료해발포<관우진일보가강항균약물림상응용관리적통지>문건후부산과위수술기항균약물적응용정황.방법 대부산과2007년4-12월272례수술환자(치료조)화2008년4-12월270례수술환자(대조조)항균약물사용정황진행비교.결과 치료조화대조조예방성항균약물사용솔분별위83.09%(226/272)、84.44%(228,270)(P>0.05);술전사용솔분별위77.94%(212/272)、85.19%(230/270)(P<0.05);항균약물응용시간분별위(5.8±2.8)、(4.5±3.8)d(P<0.01);약민시험솔분별위2.94%(8/272)、2.22%(6/270)(P>0.05);급약도경균이정맥급약위주,차균이이련위주.결론 실시<항균약물림상응용지도원칙>화<관우진일보가강항균약물림상응용관리적통지>후,항균약물적응용잉존재용약기점고、수술시간초과3 h무추가、용약시간장차이이련용약위주,존재불족지처수요다방면공동관리화개진.
Objective To investigate the utilization of antibacterials in perioperation for obstetrics and gynecology after the issuing of the notice by the general office of the Ministry of Health "further strengthen in the management of clinical application of antibacterials". Methods According to the survey on the use of antibacterials, 272 cases of surgical patients from April to December 2007 (treatment group) and 270 cases ofsurgical patients from April to December 2008 (control group) in obstetrics and gynecology department were selected,the utilization after the application of antibacterials were investigated and compared. Results The utilization rate of prophylactic use of antibacterials in treatment group and control group were 83.09% (226/272), 84.44%(228/270) respectively (P>0.05). Preoperative use were 77.94%(212/272), 85.19% (230/270) respectively (P< 0.05). The time of medication were (5.8 ± 2.8) d and (4.5 ± 3.8) d respectively (P<0.0l). Drug sensitivity rates were 2.94%(8/272), 2.22%(6/270) respectively (P>0.05). Both used intravenous as the main administration route, double therapy used as the major drug combination. Conclusions Comparison of utilization of antibacterials in perioperation for obstetrics and gynecology before and after the enforcement of "the guiding principle of clinical use of antibacterials" and "further strengthen in the management of clinical application of antibacterials" issued by the general office of the Ministry of Health. The utilization of antibacterials exist some defects:remains high starting point for administration;without an additional if operative time exceed three hours;longer administration time and double therapy as the major drug combination. In summary,there still are some deficiencies that needs co-management and improvement
