中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2011年
13期
1764-1765
,共2页
陈辉%张新力%肖海鹰%于海波%武永峰
陳輝%張新力%肖海鷹%于海波%武永峰
진휘%장신력%초해응%우해파%무영봉
宫颈肿瘤%化学栓塞,治疗性%放射疗法,调强适形
宮頸腫瘤%化學栓塞,治療性%放射療法,調彊適形
궁경종류%화학전새,치료성%방사요법,조강괄형
Uterine cervical Neoplasms%Chemoembolization,therapeutic%Radiotherapy,intensity-modulated
目的 探讨介入栓塞化疗在中晚期宫颈癌治疗中的疗效.方法 136例中晚期宫颈癌患者随机分为对照组(放疗组)68例和观察组(介入栓塞化疗组)68例,将两组患者的总有效率、不良反应发生率、二期手术率及治疗前后的血清癌胚抗原(CA125)、鳞状细胞癌抗原(SCC)、细胞角质素19(CY211)水平进行统计及比较.结果 观察组的治疗总有效率(83.8%比66.2%)及二期手术率(89.7%比48.5%)均高于对照组,不良反应发生率低于对照组(63.2%比73.5%),血清CA125[(37.89±16.78)比(52.36±16.98)U/ml]、SCC[(0.68±0.42)比(1.52±0.36)μg/L]及CY211[(4.86±2.21)比(8.45±2.85)ng/L]水平低于对照组(P＜0.05或P＜0.01).结论 介入栓塞化疗在中晚期宫颈癌中的综合疗效较佳,为中晚期宫颈癌的有效治疗方法之一.
目的 探討介入栓塞化療在中晚期宮頸癌治療中的療效.方法 136例中晚期宮頸癌患者隨機分為對照組(放療組)68例和觀察組(介入栓塞化療組)68例,將兩組患者的總有效率、不良反應髮生率、二期手術率及治療前後的血清癌胚抗原(CA125)、鱗狀細胞癌抗原(SCC)、細胞角質素19(CY211)水平進行統計及比較.結果 觀察組的治療總有效率(83.8%比66.2%)及二期手術率(89.7%比48.5%)均高于對照組,不良反應髮生率低于對照組(63.2%比73.5%),血清CA125[(37.89±16.78)比(52.36±16.98)U/ml]、SCC[(0.68±0.42)比(1.52±0.36)μg/L]及CY211[(4.86±2.21)比(8.45±2.85)ng/L]水平低于對照組(P＜0.05或P＜0.01).結論 介入栓塞化療在中晚期宮頸癌中的綜閤療效較佳,為中晚期宮頸癌的有效治療方法之一.
목적 탐토개입전새화료재중만기궁경암치료중적료효.방법 136례중만기궁경암환자수궤분위대조조(방료조)68례화관찰조(개입전새화료조)68례,장량조환자적총유효솔、불량반응발생솔、이기수술솔급치료전후적혈청암배항원(CA125)、린상세포암항원(SCC)、세포각질소19(CY211)수평진행통계급비교.결과 관찰조적치료총유효솔(83.8%비66.2%)급이기수술솔(89.7%비48.5%)균고우대조조,불량반응발생솔저우대조조(63.2%비73.5%),혈청CA125[(37.89±16.78)비(52.36±16.98)U/ml]、SCC[(0.68±0.42)비(1.52±0.36)μg/L]급CY211[(4.86±2.21)비(8.45±2.85)ng/L]수평저우대조조(P＜0.05혹P＜0.01).결론 개입전새화료재중만기궁경암중적종합료효교가,위중만기궁경암적유효치료방법지일.
Objective To study the comprehensive therapeutic effect of interventional embolization chemotherapy in advanced cervical cancer. Methods 136 patients with advanced cervical cancer were selected as research object,and they were randomly divided into control group(radiotherapy group) 68 cases and observation group(interventional embolization chemotherapy group) 68 cases,then the total effective rate,incidence of adverse reactions,secondary operation rate and serum CA125 ,SCC and CY211 of two groups before and after the treatment were analyzed and compared. Results The total effective rate( 83. 8% vs 66. 2% ) and secondary operation rate(89.7% vs 48.5% )of observation group was higher than that of control group, incidence of adverse reactions (63.2% vs73.5 % ) was lower than that of control group,serum CA125 [(37. 89 ± 16. 78) vs(52. 36 ± 16. 98) U/ml], SCC[(0. 68 ± 0. 42) vs (1.52±0.36)μg/L]and CY211[(4.86 ±2.21)vs(8.45 ±2.85)ng/L]were all lower than those of control group. ( P ＜0.05 or P ＜0.01) , there were significant differences. Conclusion The comprehensive therapeutic effect of interventional embolization chemotherapy in advanced cervical cancer was better,and it was one of effective methods in advanced cervical cancer.
