中国癌症研究(英文版)
中國癌癥研究(英文版)
중국암증연구(영문판)
CHINESE JOURNAL OF CANCER RESEARCH
2003年
2期
98-101
,共4页
许晓华%徐荣臻%王世炯%郑树%朱宁希%周旋
許曉華%徐榮臻%王世炯%鄭樹%硃寧希%週鏇
허효화%서영진%왕세형%정수%주저희%주선
Gene expression%Retrovirus%Acute myeloid leukemia
Objective: To explore the potentiality of retroviral etiology in human acute myeloid leukemia(AML). Methods: The expression of clone 6#11 in leukemic cell samples from 19 AML cases and peripheral blood mononuclear cells (PBMNCs) from 20 controls was studied by means of Northern blot and reversal transcription polymerase chain reaction (RT-PCR). Results: Northern blot and RT-PCR analyses showed that the expression level of clone 6#11 was significantly higher in AML patients than that in control. Conclusion: Northern blot and RT-PCR analyses revealed that the expression of novel retrovirus were associated with acute myeloid leukemia.