中国男科学杂志
中國男科學雜誌
중국남과학잡지
CHINESE JOURNAL OF ANDROLOGY
2010年
3期
39-42
,共4页
王利红%田姗%钟景琦%连方
王利紅%田姍%鐘景琦%連方
왕리홍%전산%종경기%련방
精子注射%细胞质内%精子%受精%胚胎发育%精液
精子註射%細胞質內%精子%受精%胚胎髮育%精液
정자주사%세포질내%정자%수정%배태발육%정액
sperm injections,intracytoplasmic%fertilization%embryonic development%semen
目的 探讨不同精液质量的ICSI(卵泡浆内单精子显微注射)周期中卵子受精与胚胎发育潜能间的差异.方法 采用回顾性资料分析的方法,比较了中心71例ICSI治疗周期.女方正常者根据精液质量分为严重少弱畸精子组(A组,n=31)与非严重少弱畸精子组(B组,n=24),非严重少弱畸精子组合并女方异常为C组(n=16).从形态学方面评估三组中受精率、(two pronuclear,2PN)率、异常受精率、未受精率、卵裂率、可用胚胎率、优质胚胎率、不可用胚胎率等实验室指标间的差异.结果 三组在卵子受精率、2PN率、异常受精率、未受精率、卵裂率、可用胚率、优质胚胎率和不可用胚胎率等方面比较,差异均无统计学意义(P＞0.05).但B组的受精率(72.29±23.1 2)低于C组(85.49±1 8.59),两组差异有统计学意义(P＜0.05);未受精率B组(22.81±22.83)高于C组(14.51±18.59),两组差异有统计学意义(P＜0.05).结论 从形态学上看,ICSI前的精液质量对卵子受精及胚胎发育没有明显影响.
目的 探討不同精液質量的ICSI(卵泡漿內單精子顯微註射)週期中卵子受精與胚胎髮育潛能間的差異.方法 採用迴顧性資料分析的方法,比較瞭中心71例ICSI治療週期.女方正常者根據精液質量分為嚴重少弱畸精子組(A組,n=31)與非嚴重少弱畸精子組(B組,n=24),非嚴重少弱畸精子組閤併女方異常為C組(n=16).從形態學方麵評估三組中受精率、(two pronuclear,2PN)率、異常受精率、未受精率、卵裂率、可用胚胎率、優質胚胎率、不可用胚胎率等實驗室指標間的差異.結果 三組在卵子受精率、2PN率、異常受精率、未受精率、卵裂率、可用胚率、優質胚胎率和不可用胚胎率等方麵比較,差異均無統計學意義(P＞0.05).但B組的受精率(72.29±23.1 2)低于C組(85.49±1 8.59),兩組差異有統計學意義(P＜0.05);未受精率B組(22.81±22.83)高于C組(14.51±18.59),兩組差異有統計學意義(P＜0.05).結論 從形態學上看,ICSI前的精液質量對卵子受精及胚胎髮育沒有明顯影響.
목적 탐토불동정액질량적ICSI(란포장내단정자현미주사)주기중란자수정여배태발육잠능간적차이.방법 채용회고성자료분석적방법,비교료중심71례ICSI치료주기.녀방정상자근거정액질량분위엄중소약기정자조(A조,n=31)여비엄중소약기정자조(B조,n=24),비엄중소약기정자조합병녀방이상위C조(n=16).종형태학방면평고삼조중수정솔、(two pronuclear,2PN)솔、이상수정솔、미수정솔、란렬솔、가용배태솔、우질배태솔、불가용배태솔등실험실지표간적차이.결과 삼조재란자수정솔、2PN솔、이상수정솔、미수정솔、란렬솔、가용배솔、우질배태솔화불가용배태솔등방면비교,차이균무통계학의의(P＞0.05).단B조적수정솔(72.29±23.1 2)저우C조(85.49±1 8.59),량조차이유통계학의의(P＜0.05);미수정솔B조(22.81±22.83)고우C조(14.51±18.59),량조차이유통계학의의(P＜0.05).결론 종형태학상간,ICSI전적정액질량대란자수정급배태발육몰유명현영향.
Objective To assess the effect of sperm quality on oocyte fertilization and embryo developmental potential via intra-cytoplasmic sperm injection.Methods Retrospective analysis was performed for the study of ICSI cycles of 71 cases.According to sperm quality and female factor for ICSI, all cases were divided into group A (n=31,with male factors and normal female), group B(n=24, with non-male factors and normal female) and group C (n=16,with non-male factors and abnormal female).The rates of fertilization, 2PN fertilization, abnormal fertilization, failed fertilization, embryo cleavage, useful embryos, good embryos and discarded embryos were evaluated based on the view of morphology.Results No significant differences in the rates of fertilization, 2PN fertilization,abnormal fertilization, failed fertilization, cleavage, useful embryos, good embryos and discarded embryos were found among three groups(P＞0.05).However,rates of fertilization in group B was lower than that in group C (72.29±23.12 Vs 85.49±18.59, P＜0.05), and the rate of failed fertilization in group B was higher than that in group C(22.81±22.83 Vs 14.51±18.59, P＜0.05).Conclusion Based on the analysis of morphology, the sperm quality might not be an important factor in oocyte fertilization and embryo development during ICSI cycles.
