CAJ | 학술논문

目的:探讨运用多巴酚丁胺负荷超声心动图(DSE)和硝酸甘油负荷单光子发射计算机断层灌注显像(SPECT)来评价经皮冠状动脉介入(PCI)术后再狭窄的价值.方法:39例PCI术后的患者,在冠状动脉造影前1周内接受DSE和SPECT检查,多巴酚丁胺剂量递增方案为5μg·kg-1·min-1,10μg·kg-1·min-1,20μg·kg-1·min-1,30 μg·kg-1·min-1,40 μg·kg 1·min-1五个级别,每级负荷维持3min.按照冠脉造影的结果确定DSE,SPECT的敏感性、特异性和准确度,分析比较DSE,SPECT和冠脉造影检查的结果.结果:与冠脉造影相比,SPECT、DSE检查评价PCI术后再狭窄的敏感性(83.3％比75.0％),准确性(71.8％比87.2％)无显著差异P＞0.05,但与SPECT相比,DSE检查的特异性较高(66.7％比92.6％),P＜0.05.结论:多巴酚丁胺负荷超声心动图评价经皮冠状动脉介入术后再狭窄准确,且特异性好于SPECT.
목적:탐토운용다파분정알부하초성심동도(DSE)화초산감유부하단광자발사계산궤단층관주현상(SPECT)래평개경피관상동맥개입(PCI)술후재협착적개치.방법:39례PCI술후적환자,재관상동맥조영전1주내접수DSE화SPECT검사,다파분정알제량체증방안위5μg·kg-1·min-1,10μg·kg-1·min-1,20μg·kg-1·min-1,30 μg·kg-1·min-1,40 μg·kg 1·min-1오개급별,매급부하유지3min.안조관맥조영적결과학정DSE,SPECT적민감성、특이성화준학도,분석비교DSE,SPECT화관맥조영검사적결과.결과:여관맥조영상비,SPECT、DSE검사평개PCI술후재협착적민감성(83.3％비75.0％),준학성(71.8％비87.2％)무현저차이P＞0.05,단여SPECT상비,DSE검사적특이성교고(66.7％비92.6％),P＜0.05.결론:다파분정알부하초성심동도평개경피관상동맥개입술후재협착준학,차특이성호우SPECT.
Objective:To study clinical application value of dobutamine stress echocardiography (DSE) and nitroglycerin stress single photon emission computed tomography (SPECT) for evaluation of restenosis after percutaneous coronary intervention (PCI).Methods:A total of 39 patients after PCI were examined by DSE and SPECT one week before coronary angiography (CAG).Dose incremental program of dobutamine included five levels:5μg ·kg-1 · min-1,10μg · kg-1 · min-1,20μg · kg-1 · min-1,30μg · kg-1 · min-1,40μg · kg-1 · min-1,and each level maintained for three minutes.Sensitivity,specificity and accuracy of DSE and SPECT were determined according to CAG examined result and examined results were compared between DSE and SPECT.Results:Compared with CAG,SPECT and DSE were no significant differences (P＞0.05) in sensitivity (83.3％ vs.75.0％) and accuracy (71.8％ vs.87.2％) for evaluating restenosis after PCI,but compared with SPECT,DSE possessed higher specificity (66.7％ vs.92.6％).Conclusions:Dobutamine stress echocardiography is accurate,and its specificity is better than that of SPECT for evaluating restenosis after percutaneous coronary intervention.