CAJ | 학술논문

目的了解北京地区正常妊娠(NG)、妊娠糖耐量受损(GIGT)、妊娠糖尿病(GDM)孕妇的糖耐量水平.方法5家医院联合前瞻性对948名孕妇在孕24～32周间先行50 g糖筛查试验,不管其值高低均于3 d后行口服葡萄糖耐量试验(OGTT). 结果OGTT按美国国家糖尿病资料组(NDDG)标准判断正常组534名,取其4次血糖值的第97.5百分位数为5.28、9.75、6.61和6.78 mmol/L.OGTT中1项异常或2 h血糖值在6.67～9.11mmol/L之间为GIGT组372名,第97.5百分位数血糖值为6.06、11.89、9.61、和8.00mmol/L.GDM组42例,其中33例根据OGTT 4项值中≥2项异常确诊,其血糖值为8.00、16.89、14.44和11.67 mmol/L.结论正常孕妇OG-TT第97.5百分位数的血糖值低于国内外报道.目前应用的NDDG诊断标准是否过高导致假阴性,有待进一步调查研究.
목적료해북경지구정상임신(NG)、임신당내량수손(GIGT)、임신당뇨병(GDM)잉부적당내량수평.방법5가의원연합전첨성대948명잉부재잉24～32주간선행50 g당사사시험,불관기치고저균우3 d후행구복포도당내량시험(OGTT). 결과OGTT안미국국가당뇨병자료조(NDDG)표준판단정상조534명,취기4차혈당치적제97.5백분위수위5.28、9.75、6.61화6.78 mmol/L.OGTT중1항이상혹2 h혈당치재6.67～9.11mmol/L지간위GIGT조372명,제97.5백분위수혈당치위6.06、11.89、9.61、화8.00mmol/L.GDM조42례,기중33례근거OGTT 4항치중≥2항이상학진,기혈당치위8.00、16.89、14.44화11.67 mmol/L.결론정상잉부OG-TT제97.5백분위수적혈당치저우국내외보도.목전응용적NDDG진단표준시부과고도치가음성,유대진일보조사연구.
Objective To investigate the glucose tolerance le vel among pregnant women in Beijing. Methods After 50 g g lucose challenge test (GCT) was done, a prospective study of 75 g oral gluco se tolerance test (OGTT) in 948 pregnant women between 24～32 gestational weeks w as done in five hospitals so as to investigate the glucose tolerance levels in n ormal, GIGT, GDM women. Results By the judgement of diagn ostic criteria of NDDG, 534 patients’OGTT were normal. The 97.5 th perce ntage of their plasma glucose level (mmol/L) were 5.28, 9.75, 6.61 and 6.78 . The 372 GIGT patients were diagnosed by OGTT, the glucose levels were 6.06, 11.89 ,9.61 and 8.00 mmol/L. 42 patients were GDM and 33 of them were di agnosed by OGTT. Their plasma glucose levels in 97.5 th percentage were 8 .00,16.89,14.44 and 11.67 mmol/L. Conclusions The 97.5 th percentages of OGTT in normal pregnant women are lower in our study than those in domestic and international reports. It needs further research to d etermine if the present NDDG diagnostic standard were too high so that it will i ncrease false negative rate.