CAJ | 학술논문

抗凝血酶-Ⅲ是人体内最霞要的天然抗凝物质,其抗凝作用占体内总抗凝作用的50％～70％.近年来研究发现,抗凝血酶Ⅲ除了具有较强的抗凝作用外,还有另一种重要的分子生物学特性,即强大的抗炎作用.本文主要对近年来抗凝血酶Ⅲ抗炎机制的研究进展进行综述.
항응혈매-Ⅲ시인체내최하요적천연항응물질,기항응작용점체내총항응작용적50％～70％.근년래연구발현,항응혈매Ⅲ제료구유교강적항응작용외,환유령일충중요적분자생물학특성,즉강대적항염작용.본문주요대근년래항응혈매Ⅲ항염궤제적연구진전진행종술.
Antithrombin-Ⅲ (AT-Ⅲ ),a physiological serine protease inhibitor,plays a critical role in the regulation of the coagulation cascade in human being.In addition to regulatory role in the coagulation system,AT-Ⅲ exerts a strong anti-inflammatory activity.This paper reviews the advancement of mechanism of AT-Ⅲ anti-inflammatory property in recent years.