CAJ | 학술논문

目的探讨高压氧治疗急性一氧化碳中毒迟发性脑病(DEAC MP)的疗效.方法对112例第四军医大学唐都医院2000年11月至2007年3月住院确诊为DEACMP的患者进行随机分组,对照组采用常规综合治疗36例,治疗组采用综合治疗加高压氧治疗76例,治疗4个疗程后评价其疗效.疗效分为1)痊愈:临床症状体征消失,脑电图恢复正常,生活自理,能胜任日常工作劳动.(2)好转:症状体征部分消失或减轻,脑电图异常程度减轻,生活部分自理,但不能胜任日常卫作.(3)无效:病情无好转或减轻.并对结果进行χ2检验与t检验.结果治疗组痊愈62例(81.58%),好转9例(11.84%),无效5例(6.94%),有效率为93.42%;对照组痊愈21例(58.33%),好转5例(13.89%),无效10例(27.78%),有效率为72.22%,治疗组有效率明显高于对照组(P＜0.05).治愈时间较对照组缩短,差异具有统计学意义(P＜0.05).结论高压氧治疗可提高急性一氧化碳中毒后迟发性脑病的疗效.
목적 탐토고압양치료급성일양화탄중독지발성뇌병(DEAC MP)적료효.방법 대112례제사군의대학당도의원2000년11월지2007년3월주원학진위DEACMP적환자진행수궤분조,대조조채용상규종합치료36례,치료조채용종합치료가고압양치료76례,치료4개료정후평개기료효.료효분위1)전유:림상증상체정소실,뇌전도회복정상,생활자리,능성임일상공작노동.(2)호전:증상체정부분소실혹감경,뇌전도이상정도감경,생활부분자리,단불능성임일상위작.(3)무효:병정무호전혹감경.병대결과진행χ2검험여t검험.결과 치료조전유62례(81.58%),호전9례(11.84%),무효5례(6.94%),유효솔위93.42%;대조조전유21례(58.33%),호전5례(13.89%),무효10례(27.78%),유효솔위72.22%,치료조유효솔명현고우대조조(P＜0.05).치유시간교대조조축단,차이구유통계학의의(P＜0.05).결론 고압양치료가제고급성일양화탄중독후지발성뇌병적료효.
Objective To study the efficacy of hyperbaric oxygen(HO)for the delayed encephalopathy after acute carbon monoxide poisoning(DEACMP)Method One hundred and eleven patients who were diagnozed as the DEACMP from November 2000 to March 2007 in Tangdu Hospital the Fourth Military Medical University were randomly divided into two groups.Thirty-six cases were treated by onventional approach(group A),and 76 cases by HO besides conventional treatment(group B).The efficacy of HO was evaluated after 4courses of treatment. The curative effects were evaluated as(1)cured:clinical symptoms and signs fully disappeared,abnormal electroencephalogram recovered,patients were completely self-help and competent enough for routine work.(2)improved:chnical symptoms and signs partly disappeared,abnormal electroencephalogram partly recovered,patients were partial self-help and incompetent enough for routine work.(3)inefficacy:patient's condition didn't changed.Data were expressed as((x)±s)and analyzed with the chi-quare test and t-test.The statistical significance was established as P＜0.05.Results In group B,62(81.58%)were in good recover,9(11.84%)improved and 5(6.94%)were inefficacy;while in group A:21(58.33%)were in good recover,5(13.89%)were improved and 10(27.78%)were inefficacy.The effciency rate in group B was significantly higher(93.42%)than that(72.22%)in group A(P＜0.05),and the required time for the therapeutic effect noticed time in group B were significantly shorter(P＜0.05)Conclusions HO Can improve the therapeutic effects on DEACMP