中国医药
中國醫藥
중국의약
CHINA MEDICINE
2011年
5期
539-540
,共2页
乐颖娟%张江蓉%卢维晟%李东霞%高艳红%沈忠梅%王一尘
樂穎娟%張江蓉%盧維晟%李東霞%高豔紅%瀋忠梅%王一塵
악영연%장강용%로유성%리동하%고염홍%침충매%왕일진
糖尿病,2型%糖化血红蛋白%血脂
糖尿病,2型%糖化血紅蛋白%血脂
당뇨병,2형%당화혈홍단백%혈지
Diabetes,type 2%Glycated hemoglobin%Lipid
目的 了解2型糖尿病患者糖化血红蛋白(HbAlc)达标对血脂的影响,探讨糖脂代谢的关联性.方法 完全随机抽取上海市殷行社区95例2型糖尿病患者的糖化血红蛋白、血脂,按HbAlc≤6.5%和HbAlc≥7.0%分成2组,其中HBAlc达标组34例,HbAlc未达标组45例,比较2组的血脂情况,同时进行HbAlc与血脂的相关性分析.结果 未达标组患者TC,TG,HDL-C,LDL-C明显高于达标组[分别为(5.42±1.04)mmol/L比(5.06±1.07)mmol/L、(2.90 ±1.59)mmol/L比(2.03±1.48)mmol/L、(1.09±0.14)mmol/L比(1.05±0.17)mmol/L、(3.16±0.58)mmol/L比(2.92±0.62)mmol/L],且TG升高有统计学意义(P<0.05).达标组TC,TG,LDH-C达标率明显高于未达标组[分别为5例(14.7%)比3例(6.7%)、17例(50.0%)比10例(22.2%)、6例(17.6%)比3例(6.7%),P<0.05].单因素分析结果表明HbAlc与TC、TG、LDH-C呈正相关(r=0.208、0.438、0.222,均P<0.05).结论 降低HbAlc可有效降低,TC、TG、LDL-C,同时HbAlc达标可以明显提高TG的达标率,2型糖尿病患者应定期监测HbAlc,控制HbAlc在正常水平.
目的 瞭解2型糖尿病患者糖化血紅蛋白(HbAlc)達標對血脂的影響,探討糖脂代謝的關聯性.方法 完全隨機抽取上海市慇行社區95例2型糖尿病患者的糖化血紅蛋白、血脂,按HbAlc≤6.5%和HbAlc≥7.0%分成2組,其中HBAlc達標組34例,HbAlc未達標組45例,比較2組的血脂情況,同時進行HbAlc與血脂的相關性分析.結果 未達標組患者TC,TG,HDL-C,LDL-C明顯高于達標組[分彆為(5.42±1.04)mmol/L比(5.06±1.07)mmol/L、(2.90 ±1.59)mmol/L比(2.03±1.48)mmol/L、(1.09±0.14)mmol/L比(1.05±0.17)mmol/L、(3.16±0.58)mmol/L比(2.92±0.62)mmol/L],且TG升高有統計學意義(P<0.05).達標組TC,TG,LDH-C達標率明顯高于未達標組[分彆為5例(14.7%)比3例(6.7%)、17例(50.0%)比10例(22.2%)、6例(17.6%)比3例(6.7%),P<0.05].單因素分析結果錶明HbAlc與TC、TG、LDH-C呈正相關(r=0.208、0.438、0.222,均P<0.05).結論 降低HbAlc可有效降低,TC、TG、LDL-C,同時HbAlc達標可以明顯提高TG的達標率,2型糖尿病患者應定期鑑測HbAlc,控製HbAlc在正常水平.
목적 료해2형당뇨병환자당화혈홍단백(HbAlc)체표대혈지적영향,탐토당지대사적관련성.방법 완전수궤추취상해시은행사구95례2형당뇨병환자적당화혈홍단백、혈지,안HbAlc≤6.5%화HbAlc≥7.0%분성2조,기중HBAlc체표조34례,HbAlc미체표조45례,비교2조적혈지정황,동시진행HbAlc여혈지적상관성분석.결과 미체표조환자TC,TG,HDL-C,LDL-C명현고우체표조[분별위(5.42±1.04)mmol/L비(5.06±1.07)mmol/L、(2.90 ±1.59)mmol/L비(2.03±1.48)mmol/L、(1.09±0.14)mmol/L비(1.05±0.17)mmol/L、(3.16±0.58)mmol/L비(2.92±0.62)mmol/L],차TG승고유통계학의의(P<0.05).체표조TC,TG,LDH-C체표솔명현고우미체표조[분별위5례(14.7%)비3례(6.7%)、17례(50.0%)비10례(22.2%)、6례(17.6%)비3례(6.7%),P<0.05].단인소분석결과표명HbAlc여TC、TG、LDH-C정정상관(r=0.208、0.438、0.222,균P<0.05).결론 강저HbAlc가유효강저,TC、TG、LDL-C,동시HbAlc체표가이명현제고TG적체표솔,2형당뇨병환자응정기감측HbAlc,공제HbAlc재정상수평.
Objective To understand the influence of lipid by up to standard type 2 diabet glycated hemogloobin and to discuss the relationship of saccharide metabolism and lipid metabolism.Methods Ninty-five patients with type 2 diabetes in Shanghai Yin-line Community were divided into two groups(HbAlc≤6.5 and HbAlc>7.0),the level of blood lipid in the two groups were compared.Meanwhile,95 patients in the glycosylated hemo globin and the corre8ponding blood were analyzed. Results TC,TG,HDL-C,LDL-C of substandard group [(5.42±1.04)mmoL/L vs(5.06±1.07)mmol/L,(2.90±1.59)mmol/L vs(2.03 ±1.48)mmol/L,(1.09±0.14)mmoL/L vs(1.05±0.17)mmol/L,(3.16 ±0.58)mmol/L vs(2.92±0.62)mmol/L,respectively J were higher than those in standard group.TG of substandard group was significantly elevated(P<0.05).The standard rate of TC,TG,HDL-C in standard group were higher than those in substandard group[5 cases(14.7%)vs 3 cases(6.4%),17 cases(50.0%)vs 10 cases(22.2%),6 cases(17.6%)vs 3 cases(6.7%),P<0.05].Univariate analy8is showed that HbAlc and TC,TG,LDH-C was positively correlated(r=0.208,0.438,0.222,both P<0.05).Conclusions HbAlc reduction can effectively reduce TC,TG,LDL-C,while the standard of HbAlc can significanty improve the standard rate of TG.Type 2 diabetes should have regular monitoring of glycated hemoglobin and HbAl c should be controlled at normal levels.
