CAJ | 학술논문

目的观察新型止血材料AristaTM控制神经外科手术中活动性出血及局部渗血的效果,并探讨其在神经外科手术的适应证.方法选择空军总医院神经外科自2008年4月至2009年5月行手术治疗的48例患者,按随机数字表法分为试验组24例和对照组24例.试验组术中使用AristaTM止血,对照组采用明胶海绵压迫止血.观察并比较两组止血时间及效果.结果 48例患者出血部位的止血均获成功,试验组止血时间为(1.88±0.74)min,对照组为(3.38±0.92)min,两组比较差异有统计学意义(Z=4.711,P=0.001).结论新型止血材料AxistaTM可以强效迅速的控制神经外科手术中出现的活动性出血及局部渗血,且优于明胶海绵压迫止血和常规手术操作技术,有较好的临床推广价值.
목적 관찰신형지혈재료AristaTM공제신경외과수술중활동성출혈급국부삼혈적효과,병탐토기재신경외과수술적괄응증.방법 선택공군총의원신경외과자2008년4월지2009년5월행수술치료적48례환자,안수궤수자표법분위시험조24례화대조조24례.시험조술중사용AristaTM지혈,대조조채용명효해면압박지혈.관찰병비교량조지혈시간급효과.결과 48례환자출혈부위적지혈균획성공,시험조지혈시간위(1.88±0.74)min,대조조위(3.38±0.92)min,량조비교차이유통계학의의(Z=4.711,P=0.001).결론 신형지혈재료AxistaTM가이강효신속적공제신경외과수술중출현적활동성출혈급국부삼혈,차우우명효해면압박지혈화상규수술조작기술,유교호적림상추엄개치.
Objective To evaluate the efficacy of a novel hemostatic material AristaTM in the management of active and local bleeding in neurosurgery, and discuss the indications for its application. Methods Forty-eight patients undergoing elective craniotomy in our department between April, 2008 and May, 2009 were randomized into the test group (n=24) and control group (n=24) with intraoperative hemostatic management using AristaTM and gelatin sponge, respectively. The hemostasis time and efficacy of the two materials were compared. Results Hemostasis was effective in all the 48 patients. The mean hemostasis time in the test group and control group was 1.88±0.74 min and 3.38±0.92 min, respectively, showing a significant difference between them (Z=4.711, P=0.001). Conclusion AristaTM allows more efficient management of active and local bleeding than gelatin sponge during neurosurgeries and has great potential for clinical application.