CAJ | 학술논문

目的了解青少年近视患者高阶像差的分布规律,探讨近视程度对高阶像差的影响.方法前瞻性系列研究.对2007年8月至2007年9月在山东大学附属省立医院眼科中心应用iTrace视功能分析仪进行检测的青少年近视104例104只眼[年龄(19.9±1.34)岁,等效球镜(-4.10±2.44)D]的高阶像差进行分析.在6mm瞳孔直径下测量3-6阶Zernike系数,计算各阶均方根(RMS)值、3～6阶总RMS值、球差(Z40,Z60)及彗差(Z3-1,Z31,Z5-1,Z51)RMS值,并分别与屈光度进行相关分析.结果受试者球镜平均为(-3.72±2.36)D,柱镜平均为(-0.77±0.62)D,总高阶像差(3～6阶)的RMS值平均为(0.433±0.176)μm,3阶至6阶的各项Zernike系数大致呈递减趋势(4阶球差Z40除外).全眼总高阶像差RMS值、3～6阶各阶RMS值和彗差RMS值均与近视程度显著相关(P＜0.01),而球差和Z60值不随屈光度变化.结论在青少年近视中,高阶像差的个体差异较大.随着近视屈光度的增加,总高阶像差和彗差呈增加趋势,使视觉成像质量下降.
목적 료해청소년근시환자고계상차적분포규률,탐토근시정도대고계상차적영향.방법 전첨성계렬연구.대2007년8월지2007년9월재산동대학부속성립의원안과중심응용iTrace시공능분석의진행검측적청소년근시104례104지안[년령(19.9±1.34)세,등효구경(-4.10±2.44)D]적고계상차진행분석.재6mm동공직경하측량3-6계Zernike계수,계산각계균방근(RMS)치、3～6계총RMS치、구차(Z40,Z60)급혜차(Z3-1,Z31,Z5-1,Z51)RMS치,병분별여굴광도진행상관분석.결과 수시자구경평균위(-3.72±2.36)D,주경평균위(-0.77±0.62)D,총고계상차(3～6계)적RMS치평균위(0.433±0.176)μm,3계지6계적각항Zernike계수대치정체감추세(4계구차Z40제외).전안총고계상차RMS치、3～6계각계RMS치화혜차RMS치균여근시정도현저상관(P＜0.01),이구차화Z60치불수굴광도변화.결론 재청소년근시중,고계상차적개체차이교대.수착근시굴광도적증가,총고계상차화혜차정증가추세,사시각성상질량하강.
Objective To investigate the distribution of high-order aberrations (HOAs, 3rd to 6th orders) in myopic eyes of young adults, and study the changes as a function of the degree of myopia. Methods Prospective studies. Using the iTrace Visual Function Analyzer, root mean square (RMS) of total HOAs, 3rd, 4th, 5th-, 6th- order aberrations, coma, and SA were computed from the central 6.0 mm zone of 104 eyes of 104 subjects (mean age 19.9±1.34years; mean manifest spherical equivalent -4.10±2.44D) in the Eye Center of Shandong Provincial Hospital Affiliated to Shandong University from August 2007 to September 2007. Correlation analysis was performed to assess the association between HOAs and refractive power. Results The mean refractive error was sphere -3.72±2.36 D and cylinder -0.77±0.62 D. The mean of the total high order RMS (3rd to 6th) was (0.433±0.176)μm.The values of Zemike coefficients progressively decreased from the 3rd-order to the 6th-order(ex-cept Z40). Significant relationships were found between myopia and total ocular high order RMS, as well as coma (P＜0.01), while the SAs and (Z40) were stable. Conclusions The ocular high order aberrations vary greatly among young adults. Total ocular high order aberration and coma increase with the degree of myopia, which decline the quality of retinal image.