中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
1期
131-132
,共2页
张爱莉%毛继芳%秦美华%冯园忠
張愛莉%毛繼芳%秦美華%馮園忠
장애리%모계방%진미화%풍완충
肾炎%紫癜%过敏性%儿童%临床%病理
腎炎%紫癜%過敏性%兒童%臨床%病理
신염%자전%과민성%인동%림상%병리
Nephritis%Purpura%Schoenlein-henoc%Children%Clinaic%Pathology
目的 分析儿童过敏性紫癜性肾炎(HSPN)的临床病理特点.方法 对16例HSPN患儿的血清检测、临床表现及免疫荧光、组织病理学资料进行回顾性分析.结果 13例血尿,其中9例单纯性血尿,4例合并蛋白尿;免疫荧光12例IgA阳性,7例IgG阳性,5例C3阳性,10(62.5%)例肾小球系膜增生,3例肾小球局灶增生,1例肾小球局灶增生硬化,1例肾小球局灶坏死,1新月体形成,Ⅱ级10例,Ⅲa级4例,Ⅲb级2例.临床痊愈14例,2例复发.结论 肾小球损害在绝大多数HSPN患儿中存在,且病理改变以Ⅱ、Ⅲ级为主.
目的 分析兒童過敏性紫癜性腎炎(HSPN)的臨床病理特點.方法 對16例HSPN患兒的血清檢測、臨床錶現及免疫熒光、組織病理學資料進行迴顧性分析.結果 13例血尿,其中9例單純性血尿,4例閤併蛋白尿;免疫熒光12例IgA暘性,7例IgG暘性,5例C3暘性,10(62.5%)例腎小毬繫膜增生,3例腎小毬跼竈增生,1例腎小毬跼竈增生硬化,1例腎小毬跼竈壞死,1新月體形成,Ⅱ級10例,Ⅲa級4例,Ⅲb級2例.臨床痊愈14例,2例複髮.結論 腎小毬損害在絕大多數HSPN患兒中存在,且病理改變以Ⅱ、Ⅲ級為主.
목적 분석인동과민성자전성신염(HSPN)적림상병리특점.방법 대16례HSPN환인적혈청검측、림상표현급면역형광、조직병이학자료진행회고성분석.결과 13례혈뇨,기중9례단순성혈뇨,4례합병단백뇨;면역형광12례IgA양성,7례IgG양성,5례C3양성,10(62.5%)례신소구계막증생,3례신소구국조증생,1례신소구국조증생경화,1례신소구국조배사,1신월체형성,Ⅱ급10례,Ⅲa급4례,Ⅲb급2례.림상전유14례,2례복발.결론 신소구손해재절대다수HSPN환인중존재,차병리개변이Ⅱ、Ⅲ급위주.
Objective To study the clinicopathology characteristics the clinical and pathological characteristics inchildren with henoch-schonlein purpura nephritis(HSPN). Methods The clinical,immunofluorescence and histopathologic features of 16 cases of HSPN were retrospectively studied. Results Among the 16 patients, 13 patients exhibited hematuria ,4 cases with proteinunia. Immunofluorescence study showed that 12 cases expressed IgA,7 cases expressed IgG,5 cases expressed C3. Grade Ⅱ had 62. 5% ,and grade Ⅲ had 37. 5%.Conclusion Renal glomerular lesion is a quite common finding in children with HSPN, and Grade Ⅱ and Ⅲ of pathological classification have been seen in the majority of HSPN patients.
