CAJ | 학술논문

The purpose of this experiment is to assess the effect of combination of traditional Chinese herbs with western medicines in prevention of postoperative intestinal adhesigns in rats.Five centimeters of the terminal part of the ileum were exposed and surface of the bowel was circularly stroked and then disposed of by five methods:(1) control;(2) fibrinogenase activators(varidase and urokinase) were used by the intraperitoneal route;(3) traditional Chinese herbs to activate blood and dispersed stagnation was treated by oral administration and Injektio salvia miltiorrhiza composita were used by the intraperitoneal route;(4) corticosteroid and antihistamine (dexamethasone and promethaz ine);(5) comprehensive treatment used in combination of fibrinogenase activators,corticosteroid and antihistamine with traditional Chinese herbs to activate blood and disperse stagnation.Two weeks after surgery,animals underwent further exploratory surgery and adhesions were evaluated.The results shown that combination of traditional Chinese herbs with western medicines (method V) was the most effective in prevention of postoperative intestinal adhesions.