CAJ | 학술논문

目的观察血浆置换联合连续性肾脏替代治疗妊娠期高脂血症性急性胰腺炎的临床疗效.方法对6例妊娠期高脂血症性急性胰腺炎患者采用血浆置换联合连续性肾脏替代治疗,观察治疗前、后患者的各项生化指标变化及效果.结果血浆置换联合连续性肾脏替代治疗可以缓解患者的临床症状,降低患者的病死率并能改善预后,是妊娠期高脂血症性急性胰腺炎患者有效地治疗手段之一.6例患者中5例治愈,随访至今无胰腺炎复发.1例死亡(死于多器官功能衰竭).结论血浆置换联合连续性肾脏替代治疗在高脂血症性急性胰腺炎中有着双重作用,不仅具有显著的降脂作用,还可以祛除体内的炎性介质,阻断系统性炎症反应综合征的发生,从而防止多脏器功能衰竭.
목적 관찰혈장치환연합련속성신장체대치료임신기고지혈증성급성이선염적림상료효.방법 대6례임신기고지혈증성급성이선염환자채용혈장치환연합련속성신장체대치료,관찰치료전、후환자적각항생화지표변화급효과.결과 혈장치환연합련속성신장체대치료가이완해환자적림상증상,강저환자적병사솔병능개선예후,시임신기고지혈증성급성이선염환자유효지치료수단지일.6례환자중5례치유,수방지금무이선염복발.1례사망(사우다기관공능쇠갈).결론 혈장치환연합련속성신장체대치료재고지혈증성급성이선염중유착쌍중작용,불부구유현저적강지작용,환가이거제체내적염성개질,조단계통성염증반응종합정적발생,종이방지다장기공능쇠갈.
Objective To observe effect of plasma exchange (PE) combined with continuous renal replacement therapy (CRRT) treatment of gestational hyperlipidemic acute pancreatitis' clinical curative effect.Methods To observe 6 cases of gestational hyperlipidemic acute pancreatitis patients using PE combined with CRRT before and after treatment in patients with various biochemical index change and effect.Results After PE and CRRT treatment,the clinical symptoms can be alleviated,reduce mortality.Improving the prognosis is gestational hyperlipidemic acute pancreatitis patients and effective means of treament.5 cases were cured,the follow-up showed no recurrent pancreatitis.1 patient died,died of multiple organ failure.Conclusion PE combined with CRRT in the treatment of hyperlipidemic acute pancreatitis (HLAP) has a dual role,not only have significant lipid-lowering effect,but also can eliminate in vivo inflammatory mediators,block to occurs the systemic inflammatory response syndrome and prevent multiple organ failure.