中华全科医师杂志
中華全科醫師雜誌
중화전과의사잡지
CHINESE JOURNAL OF GENERAL PRACTITIONERS
2008年
7期
459-461
,共3页
粒细胞集落刺激因子%白细胞介素-8%细菌感染%创伤和损伤
粒細胞集落刺激因子%白細胞介素-8%細菌感染%創傷和損傷
립세포집락자격인자%백세포개소-8%세균감염%창상화손상
Granulocyte colony-stimulating factor%Interleukin-8%Bacterial infections%Wounds and injuries
目的 评价粒细胞集落刺激因子、IL-8和白细胞计数对外科急性细菌感染性疾病的检测价值.方法 对就诊前未使用抗生素者抽取外周血标本3 ml,其中感染组患者36例,创伤组患者32例,并抽取30例健康成人外周血标本3 ml作为健康对照.ELISA方法检测粒细胞集落刺激因子和IL-8.结果 感染组粒细胞集落刺激因子(82±71)ng/L,较创伤组[(15±7)ng/L]和健康对照组[(7±4)ng/L]明显升高,差异有统计学意义(P＜0.01).结论 血清粒细胞集落刺激因子可作为外科急性细菌感染性疾病的敏感指标.
目的 評價粒細胞集落刺激因子、IL-8和白細胞計數對外科急性細菌感染性疾病的檢測價值.方法 對就診前未使用抗生素者抽取外週血標本3 ml,其中感染組患者36例,創傷組患者32例,併抽取30例健康成人外週血標本3 ml作為健康對照.ELISA方法檢測粒細胞集落刺激因子和IL-8.結果 感染組粒細胞集落刺激因子(82±71)ng/L,較創傷組[(15±7)ng/L]和健康對照組[(7±4)ng/L]明顯升高,差異有統計學意義(P＜0.01).結論 血清粒細胞集落刺激因子可作為外科急性細菌感染性疾病的敏感指標.
목적 평개립세포집락자격인자、IL-8화백세포계수대외과급성세균감염성질병적검측개치.방법 대취진전미사용항생소자추취외주혈표본3 ml,기중감염조환자36례,창상조환자32례,병추취30례건강성인외주혈표본3 ml작위건강대조.ELISA방법검측립세포집락자격인자화IL-8.결과 감염조립세포집락자격인자(82±71)ng/L,교창상조[(15±7)ng/L]화건강대조조[(7±4)ng/L]명현승고,차이유통계학의의(P＜0.01).결론 혈청립세포집락자격인자가작위외과급성세균감염성질병적민감지표.
Objective To evaluate the value of serum granulocyte colony-stimulating factor(G-CSF),interlukin-8(IL-8)and white blood cell count(WBC)in detecting acute surgical bacterial infections.Methods A total of 36 patients with infections and 32 with traumatic diseases admitted in Beijing Tongren Hospital without use of antibiotics before admission were recruited,as well as 30 normal healthy controls.Three milliliters of peripheral blood were collected from each of them.Serum G-CSF and IL-8 were measured by enzyme-linked immunosorbent assay(ELISA).Results Of all the 68 patients,serum G-CSF Was(82±71)ng/L in average in those with infections,significantly higher than that in those with trauma(15±7)ng/L(P＜0.01)and controls(7±4)ng/L(P＜0.01).Conclusions Serum G-CSF may be used as a sensitive indicator for acute surgical bacterial infections.
