CAJ | 학술논문

目的探讨非典型畸胎样/横纹肌样瘤的流行病学特点、发病机制、治疗以及预后.方法回顾性分析2007年9月至2008年9月于首都医科大学附属天坛医院神经外科手术治疗的7例患者临床、影像和病理资料以及术后随访情况.结果本组7例均手术切除肿瘤,1例术后放疗,2例术后放疗和化疗.6例患者死亡,术后平均生存期不超过4个月.存活的1例患者术后10个月肿瘤已复发.结论非典型畸胎样/横纹肌样瘤是颅内罕见的高度恶性肿瘤,尽管采取了综合治疗措施,患者预后极差.
목적 탐토비전형기태양/횡문기양류적류행병학특점、발병궤제、치료이급예후.방법 회고성분석2007년9월지2008년9월우수도의과대학부속천단의원신경외과수술치료적7례환자림상、영상화병리자료이급술후수방정황.결과 본조7례균수술절제종류,1례술후방료,2례술후방료화화료.6례환자사망,술후평균생존기불초과4개월.존활적1례환자술후10개월종류이복발.결론 비전형기태양/횡문기양류시로내한견적고도악성종류,진관채취료종합치료조시,환자예후겁차.
Objective To discuss the epidemiology and clinical features of atypical teratoid/ rhabdoid tumor( AT/RT) and to explore its pathogenesis,treatment,and prognosis. Method A retrospective review was conducted in 7 patients with surgically and pathologically verified AT/RT. Results Total or subtotal removal was achieved in 7 cases. 1 case received radiotherapy and 2 cases received both radiotherapy and chemotherapy. Six patients died with mean survival time of less than 4 months after operation. One patient suffered from tumor recurrence at the follow-up of 10 months after operation. Conclusions AT/RT is rare and highly malignant in central nervous system. Its prognosis is bad, although comprehensive therapy is achieved.