CAJ | 학술논문

目的探讨结核性胸腔积液诊断模拟评分系统.方法采用病例对照研究的方法选择结核性胸腔积液患者77例作为病例组,非结核性胸腔积液患者41例作为对照组.选择与结核性胸腔积液相关的危险因素和症状进行多元Logistic分析,计算各变量的权重分值,建立临床诊断模拟评分系统.应用受试者工作特征曲线确定结核性胸腔积液患者的评分最佳临界值.结果根据此诊断模拟评分系统对两组进行评分,病例组平均(17±6)分,对照组平均(4±3)分,两组比较差异有统计学意义(P＜0.O1).选取评分8.5分作为鉴别结核性胸腔积液和非结核性胸腔积液的临界值,当评分≥8.5分时诊断结核性胸腔积液的敏感度是90.91％ (70/77),特异度是95.12％(39/41),诊断准确度是92.37％ (109/118).结论结核性胸腔积液诊断模拟评分系统有助于结核性胸腔积液的早期诊断,特别对基层医院和非结核专业医生,有待于进一步扩大研究.
목적 탐토결핵성흉강적액진단모의평분계통.방법 채용병례대조연구적방법선택결핵성흉강적액환자77례작위병례조,비결핵성흉강적액환자41례작위대조조.선택여결핵성흉강적액상관적위험인소화증상진행다원Logistic분석,계산각변량적권중분치,건립림상진단모의평분계통.응용수시자공작특정곡선학정결핵성흉강적액환자적평분최가림계치.결과 근거차진단모의평분계통대량조진행평분,병례조평균(17±6)분,대조조평균(4±3)분,량조비교차이유통계학의의(P＜0.O1).선취평분8.5분작위감별결핵성흉강적액화비결핵성흉강적액적림계치,당평분≥8.5분시진단결핵성흉강적액적민감도시90.91％ (70/77),특이도시95.12％(39/41),진단준학도시92.37％ (109/118).결론 결핵성흉강적액진단모의평분계통유조우결핵성흉강적액적조기진단,특별대기층의원화비결핵전업의생,유대우진일보확대연구.
Objective To investigate the diagnostic analogue scoring system of tuberculous pleural effusions (TPE).Methods A hospital-based case-control study was undertaken among a cohort comprised of 77 TPE patients and 41 patients with non-tuberculous pleural effusion.Symptoms and risk factors described in the data were compared between the two groups.Significant and borderline risk factors and symptoms were selected to undergo multivariate logistic regression.A high risk analogue scoring system was constructed according to the weighted numerical scores of every variable.The optimal cut off for TPE patients were determined by using the ROC curve.Results The average score was significantly higher of the TPE patients than that of the control group patients ( mean 17 ±6 vs 4 ±3,P ＜ 0.01 ).The cut off value of the analogue scoring system of TPE patients were 8.5 points,when the cut off value was higher or equal to 8.5 points,the sensitivity was 90.91％ (70/77),the specificity was 95.12％ ( 39/41 ),the diagnostic accuracy was 92.37％ (109/118 ).Conclusions The diagnostic analogue scoring system will be helpful to detect earliy TPE patients in hospital at low level,especially for non-tuberculosis professional physician. This screening strategy need to be demonstrated furtherly.