CAJ | 학술논문

通过一步简单反应合成了谷氨酰胺衍生物胶凝剂：1-十二烷基氨基-2-Boc-氨基-L-谷氨酰胺（DBLN）,1-十四烷基氨基-2-Boc-氨基-L-谷氨酰胺（TBLN）和1-十六烷基-2-Boc-氨基-L-谷氨酰胺（HBLN）.考察了这些化合物在常见溶剂中的胶凝行为,发现DBLN和HBLN能够胶凝所实验20种溶剂中的7种,而TBLN只能在其中的4种溶剂中形成稳定凝胶.通过扫描电镜研究了所得凝胶的表面形貌,发现除了胶凝剂结构,不同溶剂对凝胶形貌也有明显影响.红外光谱分析证明酰胺基团之间的氢键作用是形成凝胶的重要推动力.
통과일보간단반응합성료곡안선알연생물효응제：1-십이완기안기-2-Boc-안기-L-곡안선알（DBLN）,1-십사완기안기-2-Boc-안기-L-곡안선알（TBLN）화1-십륙완기-2-Boc-안기-L-곡안선알（HBLN）.고찰료저사화합물재상견용제중적효응행위,발현DBLN화HBLN능구효응소실험20충용제중적7충,이TBLN지능재기중적4충용제중형성은정응효.통과소묘전경연구료소득응효적표면형모,발현제료효응제결구,불동용제대응효형모야유명현영향.홍외광보분석증명선알기단지간적경건작용시형성응효적중요추동력.
Glutamine-based gelators,1-dodecylamino-2-Boc-amino-L-glutamine（DBLN）,1-tetradecyl-amino-2-Boc-amino-L-glutamine（TBLN） and 1-hexadecyl-amino-2-Boc-amino-L-glutamine（HBLN）,were simply synthesized through one-step reaction.It was found that DBLN and HBLN could gelate seven among the tested twenty solvents,but TBLN only formed stable gel in four solvents.SEM observation showed that both the structure of the gelators and the property of the solvents affected the morphology of the aerogel,obviously.FTIR spectra revealed that the hydrogen bonding between the amide groups played an important role in gel formation.