分子诊断与治疗杂志
分子診斷與治療雜誌
분자진단여치료잡지
JOURNAL OF MOLECULAR DIAGNOSIS AND THERAPY
2009年
2期
115-117
,共3页
手足口病%心肌酶%C反应蛋白%心肌损伤
手足口病%心肌酶%C反應蛋白%心肌損傷
수족구병%심기매%C반응단백%심기손상
Hand,foot and mouth disease%Myocardial enzyme%C-reactive protein%Myocardial injury
目的 探讨对手足口病(Hand,foot and mouth disease,HFMD)患儿心肌酶活性和C反应蛋白检测的意义,预防并发心肌炎的发生.方法 以30例健康儿童作对照,对51例HFMD患儿进行心肌酶及C反应蛋白检测. 结果手足口病患儿AST、LDH、CK、CK-MB、LDH-1、α-HBDH活性和CRP水平 均高于正常对照组(P<0.05或P<0.01).其中18例有心电图异常的病例,其心肌酶谱及CRP水平更是明显高于正常. 结论部分手足口病患儿存在不同程度的心肌损害,心肌酶谱及C反应蛋白可作为手足口病患儿合并心肌损伤诊断依据和观察病情及判断预后的有效指标.
目的 探討對手足口病(Hand,foot and mouth disease,HFMD)患兒心肌酶活性和C反應蛋白檢測的意義,預防併髮心肌炎的髮生.方法 以30例健康兒童作對照,對51例HFMD患兒進行心肌酶及C反應蛋白檢測. 結果手足口病患兒AST、LDH、CK、CK-MB、LDH-1、α-HBDH活性和CRP水平 均高于正常對照組(P<0.05或P<0.01).其中18例有心電圖異常的病例,其心肌酶譜及CRP水平更是明顯高于正常. 結論部分手足口病患兒存在不同程度的心肌損害,心肌酶譜及C反應蛋白可作為手足口病患兒閤併心肌損傷診斷依據和觀察病情及判斷預後的有效指標.
목적 탐토대수족구병(Hand,foot and mouth disease,HFMD)환인심기매활성화C반응단백검측적의의,예방병발심기염적발생.방법 이30례건강인동작대조,대51례HFMD환인진행심기매급C반응단백검측. 결과수족구병환인AST、LDH、CK、CK-MB、LDH-1、α-HBDH활성화CRP수평 균고우정상대조조(P<0.05혹P<0.01).기중18례유심전도이상적병례,기심기매보급CRP수평경시명현고우정상. 결론부분수족구병환인존재불동정도적심기손해,심기매보급C반응단백가작위수족구병환인합병심기손상진단의거화관찰병정급판단예후적유효지표.
Objective To evaluate the clinical significance of myocardial enzymes and C-reactive protein in the children with hand, foot and mouth disease(HFMD) and prevent myocarditis simultaneously. Methods Serum myocardial enzymes, excluding AST, LDH, CK, CK-MB, LDH-1, α-HBDH and CRP were examined in 51 cases with HTMD, and 30 healthy control group. Results The levels of serum myocardial enzymes and C-reactive protein, in the HFMD group including 18 cases with abnormal electrocardiogram were significantly higher than those in the control group (P<0.05 or P<0.01). Conclusion Different degree of myocardial injury existed in children with HFMD; myocardial enzymes and CRP could be used as a valuable marker for diagnosis, observing tendency, and predicting prognosis of myocardial injury in the children with HFMD.
