中国现代医学杂志
中國現代醫學雜誌
중국현대의학잡지
CHINA JOURNAL OF MODERN MEDICINE
2004年
17期
23-28
,共6页
中西医结合%狼疮性肾炎%荟萃分析
中西醫結閤%狼瘡性腎炎%薈萃分析
중서의결합%랑창성신염%회췌분석
integrated traditional%chinese medicine and western medicine%lupus nephritis%meta-analysis
目的验证中西医结合治疗狼疮性肾炎(LN)的临床疗效,探讨LN的有效中西医治法.方法对1990年～2002年12年间为中国生物医学文献光盘数据库收录.具有西药对照的中西医结合治疗LN论文22篇,共讲2160例LN患者(中西医结合(CW)组1186例,西医对照(W)组974例)实施荟萃分析.结果1.CW组总有效率和完全缓解率明显高于W组(94.1%vs 79.0%,34.4%vs 20.3%),无效率、死亡率、复发率和药物副作用发生率明显低于W组(5.6%vs 18.1%,0.3%vs 3.0%.5.9%vs 22.8%,27.7%vs 71.8%).2.各主要中药应用频率:白花蛇活草85.7%,紫草81 3%,半枝莲76.7%,蜈蚣,,益母草81.2%,丹参87.2%,赤芍72.0%.结论以消热解毒、活血化瘀为主体的中西医结合治疗较单纯西医治疗LN有明显优势.
目的驗證中西醫結閤治療狼瘡性腎炎(LN)的臨床療效,探討LN的有效中西醫治法.方法對1990年～2002年12年間為中國生物醫學文獻光盤數據庫收錄.具有西藥對照的中西醫結閤治療LN論文22篇,共講2160例LN患者(中西醫結閤(CW)組1186例,西醫對照(W)組974例)實施薈萃分析.結果1.CW組總有效率和完全緩解率明顯高于W組(94.1%vs 79.0%,34.4%vs 20.3%),無效率、死亡率、複髮率和藥物副作用髮生率明顯低于W組(5.6%vs 18.1%,0.3%vs 3.0%.5.9%vs 22.8%,27.7%vs 71.8%).2.各主要中藥應用頻率:白花蛇活草85.7%,紫草81 3%,半枝蓮76.7%,蜈蚣,,益母草81.2%,丹參87.2%,赤芍72.0%.結論以消熱解毒、活血化瘀為主體的中西醫結閤治療較單純西醫治療LN有明顯優勢.
목적험증중서의결합치료랑창성신염(LN)적림상료효,탐토LN적유효중서의치법.방법대1990년～2002년12년간위중국생물의학문헌광반수거고수록.구유서약대조적중서의결합치료LN논문22편,공강2160례LN환자(중서의결합(CW)조1186례,서의대조(W)조974례)실시회췌분석.결과1.CW조총유효솔화완전완해솔명현고우W조(94.1%vs 79.0%,34.4%vs 20.3%),무효솔、사망솔、복발솔화약물부작용발생솔명현저우W조(5.6%vs 18.1%,0.3%vs 3.0%.5.9%vs 22.8%,27.7%vs 71.8%).2.각주요중약응용빈솔:백화사활초85.7%,자초81 3%,반지련76.7%,오공,,익모초81.2%,단삼87.2%,적작72.0%.결론이소열해독、활혈화어위주체적중서의결합치료교단순서의치료LN유명현우세.
Objective: To evaluate the clinical effect of integrated traditional Chinese medicine and western Medicine (TCM-MW) and to investigate effective therapy of TCM for lupus nephritis (LN). Methods: We performed a me ta-analyses to analyze total 2160 patients with LN [1186 patients treated with TCM-WM (CW group) and 974 patients treated with western medicine alone (W group)] from 22 published randomized and controlled trials that were included by Chinese Biology Medicine disc from 1990 through 2002. Results: The total effective rate and the whole remission rate of CW group were significantly higher than that of W group (94.1% vs 79.0%, 34.4% vs 20.3%) and the inefficacy, mortality, recurrent rate and adverse reaction rate were much lower than W group (5.6% vs 18.1%,0.3% vs 3.0%. 5.9% vs 22.8%, 27.7% vs 71.8% respectively). 2. Frequency that major traditional Chinese medicine was used: herb of spneading hedyotis, radix arnebiae, herb of barbed skullcap, centipede, motherwort herb, root of dan-shen, radix paeoniae rubra was 85.7%, 81.3%, 76.7%, 73.3%, 81.2%, 87.2% and 72.0% respectively. Conclusions: Using clearing away heat and toxic material, activating blood circulation to dissipate as central TCM-MM therapy were obviously superior to therapy with western medicine alone.
