CAJ | 학술논문

目的探讨超声诊断胎儿先天性肾脏畸形的价值.方法对美国加州一产前诊断中心5年中做产科超声的孕妇检查结果进行分析.结果发现各种肾脏畸形占58例,其中肾发育不全者4例、多囊肾8例、梗阻引起的囊样肾畸型5例、肾与输尿管重复畸形6例、异位肾6例、肾积水18例、染色体隐性遗传的多囊肾疾病3例.染色体显性遗传的多囊肾疾病2例、先天性肾小球功能异常1例、Meckel-Gruber综合征3例、Beckwith-Wiedemann综合征2例.分析各种畸形的声像图特点,不同类型肾畸形有不同声像图表现,并与其胚胎发育过程异常相关.结论泌尿系统畸形对妊娠结果有着重要的影响,特别是伴有羊水过少时,超声能准确地发现和诊断泌尿系畸形,在诊断胎儿先天性肾脏畸形中有重要价值.了解畸形的发生原因,可更好理解其预后,为临床提供准确诊断和处理依据.
목적탐토초성진단태인선천성신장기형적개치.방법대미국가주일산전진단중심5년중주산과초성적잉부검사결과진행분석.결과발현각충신장기형점58례,기중신발육불전자4례、다낭신8례、경조인기적낭양신기형5례、신여수뇨관중복기형6례、이위신6례、신적수18례、염색체은성유전적다낭신질병3례.염색체현성유전적다낭신질병2례、선천성신소구공능이상1례、Meckel-Gruber종합정3례、Beckwith-Wiedemann종합정2례.분석각충기형적성상도특점,불동류형신기형유불동성상도표현,병여기배태발육과정이상상관.결론비뇨계통기형대임신결과유착중요적영향,특별시반유양수과소시,초성능준학지발현화진단비뇨계기형,재진단태인선천성신장기형중유중요개치.료해기형적발생원인,가경호리해기예후,위림상제공준학진단화처리의거.
Objective To assess the value of ultrasound in diagnosis of congenital renal malformations. Methods The records of obstetric ultrasound examinations were reviewed in all the pregnant women admitted in Alta Bates Perinatal Diagnostic center (Oakland, California, USA) during 5 years. Results Ultrasound examination identified 58 cases of congenital renal malformations of different kinds, including 4 cases of renal agenesis, 8 multicystic dysplastic kidney, 5 cystic renal dysplasia with obstructions, 6 renal and ureteral duplications, 6 ectopic kidneys, 18 hydronephroses, 3 autosomal recessive polycystic kidney diseases, 2 autosomal dominant polycystic diseases, 1 Finnish-type congenital nephrosis, 3 Meckel-Gruber syndromes, and 2Beckwith-Wiedemann syndromes. Different renal malformations had different ultrasound findings that correlated to abnormalities in embryonic developments. Conclusions Urinary tract abnormalities have a profound effect on pregnancy outcome, especially when associated with oligohydramnios. Many urinary anomalies can be readily detected and diagnosed by ultrasound,which provides a useful modality in diagnosis of fetal congenital renal malformations. Clear understanding of the causes of these abnormalities facilitates prognostic evaluation and clinical decision on the treatment protocol.