中国肿瘤临床与康复
中國腫瘤臨床與康複
중국종류림상여강복
CHINESE JOURNAL OF CLINICAL ONCOLOGY AND REHABILITATION
2001年
2期
74-75
,共2页
肺癌%放射性核素显像%骨转移
肺癌%放射性覈素顯像%骨轉移
폐암%방사성핵소현상%골전이
目的探讨肺癌骨转移患者骨显像的特点及规律。方法 136例肺癌患者做全身骨核素显像。结果 136例肺癌患者中有87例骨显像异常，结合临床及X线诊断为骨转移，骨转移的发生率为63.97%。其中左肺癌的阳性率为58.33%，右肺癌的阳性率为73.47%。肺腺癌的阳性率72.4 1%，肺鳞癌的阳性率为43.48%，腺癌较鳞癌容易发生骨转移(P<0.05)。87例骨转移患者中81 例为多发病灶(占93.1%)，6例为单发病灶(占6.9%)，每例患者的平均病灶数为6.39个。骨转移的部位以胸部为多见，其余依次为脊柱、骨盆、肢体和颅骨。伴有区域淋巴结及远处其它器官转移的患者出现骨显像异常的可能显著增多(P<0.05)，骨转移是否发生与肿瘤原发病灶范围之间的关系未能得到统计学证实。结论肺癌骨转移发生率很高，骨转移的发生有一定的规律及特点，核素全身骨显像对于临床诊断分期及治疗决策有一定的意义。
目的探討肺癌骨轉移患者骨顯像的特點及規律。方法 136例肺癌患者做全身骨覈素顯像。結果 136例肺癌患者中有87例骨顯像異常，結閤臨床及X線診斷為骨轉移，骨轉移的髮生率為63.97%。其中左肺癌的暘性率為58.33%，右肺癌的暘性率為73.47%。肺腺癌的暘性率72.4 1%，肺鱗癌的暘性率為43.48%，腺癌較鱗癌容易髮生骨轉移(P<0.05)。87例骨轉移患者中81 例為多髮病竈(佔93.1%)，6例為單髮病竈(佔6.9%)，每例患者的平均病竈數為6.39箇。骨轉移的部位以胸部為多見，其餘依次為脊柱、骨盆、肢體和顱骨。伴有區域淋巴結及遠處其它器官轉移的患者齣現骨顯像異常的可能顯著增多(P<0.05)，骨轉移是否髮生與腫瘤原髮病竈範圍之間的關繫未能得到統計學證實。結論肺癌骨轉移髮生率很高，骨轉移的髮生有一定的規律及特點，覈素全身骨顯像對于臨床診斷分期及治療決策有一定的意義。
목적탐토폐암골전이환자골현상적특점급규률。방법 136례폐암환자주전신골핵소현상。결과 136례폐암환자중유87례골현상이상，결합림상급X선진단위골전이，골전이적발생솔위63.97%。기중좌폐암적양성솔위58.33%，우폐암적양성솔위73.47%。폐선암적양성솔72.4 1%，폐린암적양성솔위43.48%，선암교린암용역발생골전이(P<0.05)。87례골전이환자중81 례위다발병조(점93.1%)，6례위단발병조(점6.9%)，매례환자적평균병조수위6.39개。골전이적부위이흉부위다견，기여의차위척주、골분、지체화로골。반유구역림파결급원처기타기관전이적환자출현골현상이상적가능현저증다(P<0.05)，골전이시부발생여종류원발병조범위지간적관계미능득도통계학증실。결론폐암골전이발생솔흔고，골전이적발생유일정적규률급특점，핵소전신골현상대우림상진단분기급치료결책유일정적의의。
Objective To evaluate the characteristics of skel etal metastases in lung cancer.Methods 136 patients with lung cancer were examined by radionuclide bone imaging.Results Amon g them,87 cases were identified as having skeletal metastases.The incidence of b one metastases compared with clinical data and X-ray examination was about 63.9 7%.The incidence of cancer in right lung and left lung were 73.47% and 58.33%,re spectively.The incidence of bone metastases varied with different lateral of lun g cancer (P<0.01).The incidence of adenocarcinoma (72.41%) was higher than squam ous carcinoma(43.48%)(P<0.05).Multiple metastatic lesions accounted for 93.1% (8 1 cases) and solitary 6.9% (6 cases),with an average of 6.39 loci per patient.Th e site of bone metastases was commonly seen in the thorax,followed by spine,peli vs,limbs and skull. The incidence of bone metastases increased significantly in the patients with local lymph node and or distal metastases(P<0.05).The relation between skeletal metastases and the size of original tumor remained uncertain.Conclusions Bone imaging should be performed in the patients wi th lung cancer,for its importance for evaluation of staging and treatment.
