清华大学学报(英文版)
清華大學學報(英文版)
청화대학학보(영문판)
TSINGHUA SCIENCE AND TECHNOLOGY
2001年
3期
216-221
,共6页
杨霰霜%赵锴%陈金春%夏彩虹%陈国强
楊霰霜%趙鍇%陳金春%夏綵虹%陳國彊
양산상%조개%진금춘%하채홍%진국강
The purpose of this study was to investigate in vitro biocompatibility of a new type of polymer, polyhydroxybutyrate-co-hexanoate (PHBHHx). The hydrophilicity and biocompatibility were studied with two kinds of enzymes, amylase BAN480L and lipase Novozym388. The degree of hydrophilicity was observed using contact angle measurements. In vitro biocompatibility evaluations were carried out by direct incubation of mouse fibroblast cell line L929 on the polyhydroxyalkanoate (PHA) films. The samples treated with BAN480L showed that the PHA biocompatibility increased while the hydrophilicity decreased. Relative to untreated samples, the number of cells on the Novozym388 modified PHBHHx significant decrease as the hydrophilicity also decreased. The results indicated that other surface characteristics besides hydrophilicity influence the biocompatibility of PHBHHx films.
