CAJ | 학술논문

采用巯基化合物自组装/共价键合反应的逐层固定方法将双链DNA固定到金表面得到DNA修饰电极，并对该电极表面进行了电化学和X射线光电子能谱表征. 研究了电极表面固定化DNA的表面分子杂交. 对开发电化学基因诊断芯片和基因传感器具有一定意义.
채용구기화합물자조장/공개건합반응적축층고정방법장쌍련DNA고정도금표면득도DNA수식전겁，병대해전겁표면진행료전화학화X사선광전자능보표정. 연구료전겁표면고정화DNA적표면분자잡교. 대개발전화학기인진단심편화기인전감기구유일정의의.
Double-stranded DNA was covalently immobilized onto gold surfaces by layer-by-layer immobilization method, and the surfaces were characterized by electrochemical and XPS methods. The surface molecular hybridization of DNA was studied on these functionized surfaces. This work might be fundamental for electrochemical gene chips and genosensors for disease diagnosis.