广西植物
廣西植物
엄서식물
GUIHAIA
2010年
1期
127-132
,共6页
梁梅%赵志国%卢凤来%刘金磊%陈月圆%文永新%李典鹏%孙步祥
樑梅%趙誌國%盧鳳來%劉金磊%陳月圓%文永新%李典鵬%孫步祥
량매%조지국%로봉래%류금뢰%진월원%문영신%리전붕%손보상
苦丁茶%L-阿拉伯糖%乌龙茶%肥胖症%高脂血症
苦丁茶%L-阿拉伯糖%烏龍茶%肥胖癥%高脂血癥
고정다%L-아랍백당%오룡다%비반증%고지혈증
extract of Ku-Ding-Cha%L-arabinose%extract of oolong tea%obesity%hyperlipemia
选用Wistar雄性大鼠,喂饲高脂饲料,建立预防性肥胖高血脂模型,对苦丁茶水提取物、阿拉伯糖、乌龙茶提取物三种天然成分进行减肥降脂试验.大鼠随机分组,灌胃给药,以药物曲美减肥胶囊为阳性对照组.测定模型组、给药实验组、阳性对照组各种生化指标(如总胆固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白)、大鼠的体重、Lee's指数和脂肪湿重等.结果表明:各给药实验组较模型对照组体重增长减慢,且下降明显,体内脂肪湿重也明显下降,同时发现L-阿拉伯糖组有极其显著降低血清总胆固醇、甘油三酯、低密度脂蛋白胆固醇、Lee's指数和体内脂肪含量(P<0.01)的效果.L-阿拉伯糖对肥胖症、高血脂症具有良好的预防和治疗的作用.
選用Wistar雄性大鼠,餵飼高脂飼料,建立預防性肥胖高血脂模型,對苦丁茶水提取物、阿拉伯糖、烏龍茶提取物三種天然成分進行減肥降脂試驗.大鼠隨機分組,灌胃給藥,以藥物麯美減肥膠囊為暘性對照組.測定模型組、給藥實驗組、暘性對照組各種生化指標(如總膽固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白)、大鼠的體重、Lee's指數和脂肪濕重等.結果錶明:各給藥實驗組較模型對照組體重增長減慢,且下降明顯,體內脂肪濕重也明顯下降,同時髮現L-阿拉伯糖組有極其顯著降低血清總膽固醇、甘油三酯、低密度脂蛋白膽固醇、Lee's指數和體內脂肪含量(P<0.01)的效果.L-阿拉伯糖對肥胖癥、高血脂癥具有良好的預防和治療的作用.
선용Wistar웅성대서,위사고지사료,건립예방성비반고혈지모형,대고정다수제취물、아랍백당、오룡다제취물삼충천연성분진행감비강지시험.대서수궤분조,관위급약,이약물곡미감비효낭위양성대조조.측정모형조、급약실험조、양성대조조각충생화지표(여총담고순、감유삼지、저밀도지단백화고밀도지단백)、대서적체중、Lee's지수화지방습중등.결과표명:각급약실험조교모형대조조체중증장감만,차하강명현,체내지방습중야명현하강,동시발현L-아랍백당조유겁기현저강저혈청총담고순、감유삼지、저밀도지단백담고순、Lee's지수화체내지방함량(P<0.01)적효과.L-아랍백당대비반증、고혈지증구유량호적예방화치료적작용.
70 male wistar rats were randomly divided into 7 groups according to body weight,and fed with a high fat diet and supplement to set up the model rat of obesity and hyperlipemia. Qumei medicine was used as a positive control,extract of Ku-Ding-Cha,L-arabinose and extract of oolong tea used as experimental controls to investigate their effect on body weight-reducing and secrum lipid-reducing. After continuing administration,the biochemical markers of different groups,including model control,positive control and experimental control were measured. The results showed that comparing with model control,all positive control and experimental controls could reduce the rat's body weight. Furthermore,the Lee's index,wet weight of fat,total cholesterol(TC),serum truglyceride(TG),low density lipoprotein-cholesterol(LDL-C)were significantly decreased in L-arabinose experimental group. So L-arabinose has a good anti-obesity and anti-hyperlipemia effectiveness.