实用医学杂志
實用醫學雜誌
실용의학잡지
THE JOURNAL OF PRACTICAL MEDICINE
2010年
3期
409-411
,共3页
殷兆芳%方唯一%吴士尧%严毓勤%任义荣%解玉水
慇兆芳%方唯一%吳士堯%嚴毓勤%任義榮%解玉水
은조방%방유일%오사요%엄육근%임의영%해옥수
冠心痛%利钠肽%冠脉造影%药物洗脱支架
冠心痛%利鈉肽%冠脈造影%藥物洗脫支架
관심통%리납태%관맥조영%약물세탈지가
目的:初步探讨稳定性冠心病(coronary artery disease,CAD)患者静脉血浆B型利钠肽(B-type natriuretic peptide,BNP)水平与冠脉病变的关系,以及药物洗脱支架植入前后BNP水平的变化.方法:研究入选了88例稳定性CAD,均经冠脉造影(coronary angiography,CAG)证实.收集临床、CAG和经皮冠脉介入(percutaneous coronary intervention,PCI)资料.所有入选者微粒子酶免分析法(化学发光法)测定静脉BNP浓度.其中29例在DES植入后进行了CAG复查和BNP测定.结果:BNP水平在单支病变组(123.51±18.50)pg/mL,2支病变组(148.32±34.97)pg/mL,3支病变(166.11±28.53)pg/mL,组间BNP浓度比较差异无显著性(P=0.493 3).Gensini 积分≤33组BNP水平为(118.94±16.47)pg/mL;Gensini积分＞33组为(180.59±27.35)pg/mL,P=0.046 8.DES植入8个月后BNP水平明显降低[(230.43±48.81)pg/mLvs(149.33±17.49)pg/mL,P=0.038 2].结论:冠脉痛变越重,BNP水平越高;稳定性CAD患者DES植入8个月后BNP水平明显降低.
目的:初步探討穩定性冠心病(coronary artery disease,CAD)患者靜脈血漿B型利鈉肽(B-type natriuretic peptide,BNP)水平與冠脈病變的關繫,以及藥物洗脫支架植入前後BNP水平的變化.方法:研究入選瞭88例穩定性CAD,均經冠脈造影(coronary angiography,CAG)證實.收集臨床、CAG和經皮冠脈介入(percutaneous coronary intervention,PCI)資料.所有入選者微粒子酶免分析法(化學髮光法)測定靜脈BNP濃度.其中29例在DES植入後進行瞭CAG複查和BNP測定.結果:BNP水平在單支病變組(123.51±18.50)pg/mL,2支病變組(148.32±34.97)pg/mL,3支病變(166.11±28.53)pg/mL,組間BNP濃度比較差異無顯著性(P=0.493 3).Gensini 積分≤33組BNP水平為(118.94±16.47)pg/mL;Gensini積分＞33組為(180.59±27.35)pg/mL,P=0.046 8.DES植入8箇月後BNP水平明顯降低[(230.43±48.81)pg/mLvs(149.33±17.49)pg/mL,P=0.038 2].結論:冠脈痛變越重,BNP水平越高;穩定性CAD患者DES植入8箇月後BNP水平明顯降低.
목적:초보탐토은정성관심병(coronary artery disease,CAD)환자정맥혈장B형리납태(B-type natriuretic peptide,BNP)수평여관맥병변적관계,이급약물세탈지가식입전후BNP수평적변화.방법:연구입선료88례은정성CAD,균경관맥조영(coronary angiography,CAG)증실.수집림상、CAG화경피관맥개입(percutaneous coronary intervention,PCI)자료.소유입선자미입자매면분석법(화학발광법)측정정맥BNP농도.기중29례재DES식입후진행료CAG복사화BNP측정.결과:BNP수평재단지병변조(123.51±18.50)pg/mL,2지병변조(148.32±34.97)pg/mL,3지병변(166.11±28.53)pg/mL,조간BNP농도비교차이무현저성(P=0.493 3).Gensini 적분≤33조BNP수평위(118.94±16.47)pg/mL;Gensini적분＞33조위(180.59±27.35)pg/mL,P=0.046 8.DES식입8개월후BNP수평명현강저[(230.43±48.81)pg/mLvs(149.33±17.49)pg/mL,P=0.038 2].결론:관맥통변월중,BNP수평월고;은정성CAD환자DES식입8개월후BNP수평명현강저.
