国际流行病学传染病学杂志
國際流行病學傳染病學雜誌
국제류행병학전염병학잡지
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY AND INFECTIOUS DISEASE
2011年
3期
215-217
,共3页
胎盘%滋养层细胞%细胞模型
胎盤%滋養層細胞%細胞模型
태반%자양층세포%세포모형
Placenta%Trophoblastic cells%Culture models
滋养层细胞是胎盘结构中体现其屏障作用最重要的细胞,与多种妊娠疾病的发生、发展有关.另外,大多数病毒可导致胎盘感染并波及胎儿,因此滋养层细胞与宫内传播也有关.为了阐明多种妊娠相关疾病的发病机制及病毒宫内传播的机制,目前众多研究者通过在体外建立滋养层细胞模型进行了大量有价值的研究,此文对相关的研究进展进行综述.
滋養層細胞是胎盤結構中體現其屏障作用最重要的細胞,與多種妊娠疾病的髮生、髮展有關.另外,大多數病毒可導緻胎盤感染併波及胎兒,因此滋養層細胞與宮內傳播也有關.為瞭闡明多種妊娠相關疾病的髮病機製及病毒宮內傳播的機製,目前衆多研究者通過在體外建立滋養層細胞模型進行瞭大量有價值的研究,此文對相關的研究進展進行綜述.
자양층세포시태반결구중체현기병장작용최중요적세포,여다충임신질병적발생、발전유관.령외,대다수병독가도치태반감염병파급태인,인차자양층세포여궁내전파야유관.위료천명다충임신상관질병적발병궤제급병독궁내전파적궤제,목전음다연구자통과재체외건립자양층세포모형진행료대량유개치적연구,차문대상관적연구진전진행종술.
Trophoblastic cell is one of the most important cells in placenta structure, which is realated to pregnancy diseases. In addition, infant can be infected by viruses invading through placenta, so trophoblastic cell is related to intrauterine infection. To explain the pathogenic mechanisms of the gestational diseases and the mechanism of virus intrauterine infection, many studies are made about in vitro culture model of trophoblastic cells from placenta, and the research progress about the culture model is reviewed in this article.