CAJ | 학술논문

目的探讨复发性心房颤动(AF)患者转复为窦性心律前后血浆脑钠肽(BrainNatriuretic Peptide,BNP)浓度的变化及其临床意义.方法选取心功能1～2级的无合并其他心脏病复发性AF患者30例,采用干性免疫法测定AF复律前、转复为窦性心律后患者血浆BNP浓度,比较BNP的差异.结果复律前患者血浆BNP水平为(82.3±12.1)mg/L,转复为窦性心律时患者血BNP水平为(51.5±15.2)ng/L,两者有统计学差异(P<0.05).结论复发性AF患者复律前血浆BNP的浓度增高,成功转复为窦性心律时下降,提示BNP的浓度变化可作为复发性AF的预测指标.
목적 탐토복발성심방전동(AF)환자전복위두성심률전후혈장뇌납태(BrainNatriuretic Peptide,BNP)농도적변화급기림상의의.방법 선취심공능1～2급적무합병기타심장병복발성AF환자30례,채용간성면역법측정AF복률전、전복위두성심률후환자혈장BNP농도,비교BNP적차이.결과 복률전환자혈장BNP수평위(82.3±12.1)mg/L,전복위두성심률시환자혈BNP수평위(51.5±15.2)ng/L,량자유통계학차이(P<0.05).결론 복발성AF환자복률전혈장BNP적농도증고,성공전복위두성심률시하강,제시BNP적농도변화가작위복발성AF적예측지표.
Objective The objective is to find the difference and the significance of changes of plasm Brain Natriuretic Peptide(BNP)in replayed atrial fibrillation patients before and after cardioversion. Methods 30 cases of replayed atrial fbrillation with one or two degree heart function were chosen.The concentrations of BNP were measured before, as and after atrial fibrillation.Results The concentration of BNP was (82.3 ± 12.1) ng/L before atrial fibrillation.and (51.5 ± 15.2) ng/L after atrial fibrillation cardioversion.the significant differences were noticed between the concentrations before or after atrial fibrillation cardioversion.Conclnsions The concentration of BNP increased when the replayed atrial fibrillation was outbreaking and decreased when the patients recovered to sinus rhythm.BNP may be a predictive factor for the replayed atrial fibrillation.