CAJ | 학술논문

目的:研究繁缕中的黄酮类化合物 .方法:95%的乙醇提取物的水混悬液依次用石油醚、乙酸乙酯和正丁醇萃取,各种柱层析进行分离纯化,UV, NMR 等波谱数据进行结构鉴定.[ HTH 结果:从中分离得到14 个黄酮碳苷类化合物,其结构鉴定为:芹菜素(apige nin)(1),芹菜素-6,8-二-C-β-D-吡喃葡萄糖苷 (2),即新西兰牡荆苷-2[vicenin-Ⅱ (6,8-二-C-β-D-glucopyr anosyl apigenin)],芹菜素-6-C-β-D-葡萄糖-8-C-β-D-半乳糖苷(8-C-β-D-galactopyranosylisovitexin (6-C-β-D-glu copyranosyl-8-C-β-D-galactopyranosyl apigenin)(3) ,芹菜素-6-C-β-D-半乳糖-8-C-β-D-葡萄糖苷(6-C- β-D-galactopyranosylvitexin 6-C-β-D-galactopyranosyl-8- C-β-D-glucopyranosyl apigenin)(4),芹菜素-6,8-二- C-α-L-阿拉伯糖苷(6,8-di-C-α-L-arabinopyranosyl a pigenin)(5),芹菜素-6-C-β-D-葡萄糖-8-C-α -L-阿拉伯糖苷[schaftoside (6-C-β-D-glucopyranosyl-8-C -α-L-arabinosyl apigenin)](6),芹菜素-6-C-α- L-阿拉伯糖-8-C-β-D-葡萄糖苷[isoschaftoside (6-C-α-L -arabinosyl-8-C-β-D-glucopyranosyl apigenin)](7),芹菜素-6-C-β-D-半乳糖-8-C-α-L-阿拉伯糖苷(6-C -β-D-galactopyranosyl-8-C-α-L-arabinosyl apigenin)(8),芹菜素-8-C-β-D-半乳糖(8-C-β-D-galac tosyl apigenin)(9),牡荆素[vitexin (8-C-β-D-gluco pyranosyl apigenin)](10),异牡荆素[isovitexin (6-C-β- D-glucopyranosyl apigenin)](11),麦黄酮-6,8-二-C- β-D葡萄糖苷(tricetin 6,8-di-C-β-D-glucopyranoside)(12),麦黄酮-6-C-α-L-阿拉伯糖-8-C-β-D- 葡萄糖苷[tricetin 6-C-α-L-arabinosyl-8-C-β-D-galacto pyranoside](13),7-O-β-D-葡萄糖基-6-C-β- D-葡萄糖(6″-乙酰基)芹菜素[7-O-β-D-glucopyranosyl-6-C -β-D-6″-acetyl-glucopyranosyl apigenin](14). 结论:9个化合物(3～8及12、13)为首次从该植物中分离得到, 化合物14为新化合物.
목적:연구번루중적황동류화합물 .방법:95%적을순제취물적수혼현액의차용석유미、을산을지화정정순췌취,각충주층석진행분리순화,UV, NMR 등파보수거진행결구감정.[ HTH 결과:종중분리득도14 개황동탄감류화합물,기결구감정위:근채소(apige nin)(1),근채소-6,8-이-C-β-D-필남포도당감 (2),즉신서란모형감-2[vicenin-Ⅱ (6,8-이-C-β-D-glucopyr anosyl apigenin)],근채소-6-C-β-D-포도당-8-C-β-D-반유당감(8-C-β-D-galactopyranosylisovitexin (6-C-β-D-glu copyranosyl-8-C-β-D-galactopyranosyl apigenin)(3) ,근채소-6-C-β-D-반유당-8-C-β-D-포도당감(6-C- β-D-galactopyranosylvitexin 6-C-β-D-galactopyranosyl-8- C-β-D-glucopyranosyl apigenin)(4),근채소-6,8-이- C-α-L-아랍백당감(6,8-di-C-α-L-arabinopyranosyl a pigenin)(5),근채소-6-C-β-D-포도당-8-C-α -L-아랍백당감[schaftoside (6-C-β-D-glucopyranosyl-8-C -α-L-arabinosyl apigenin)](6),근채소-6-C-α- L-아랍백당-8-C-β-D-포도당감[isoschaftoside (6-C-α-L -arabinosyl-8-C-β-D-glucopyranosyl apigenin)](7),근채소-6-C-β-D-반유당-8-C-α-L-아랍백당감(6-C -β-D-galactopyranosyl-8-C-α-L-arabinosyl apigenin)(8),근채소-8-C-β-D-반유당(8-C-β-D-galac tosyl apigenin)(9),모형소[vitexin (8-C-β-D-gluco pyranosyl apigenin)](10),이모형소[isovitexin (6-C-β- D-glucopyranosyl apigenin)](11),맥황동-6,8-이-C- β-D포도당감(tricetin 6,8-di-C-β-D-glucopyranoside)(12),맥황동-6-C-α-L-아랍백당-8-C-β-D- 포도당감[tricetin 6-C-α-L-arabinosyl-8-C-β-D-galacto pyranoside](13),7-O-β-D-포도당기-6-C-β- D-포도당(6″-을선기)근채소[7-O-β-D-glucopyranosyl-6-C -β-D-6″-acetyl-glucopyranosyl apigenin](14). 결론:9개화합물(3～8급12、13)위수차종해식물중분리득도, 화합물14위신화합물.
AIM: To isolate the chemical constituents from the aerial parts of Stellaria media(L.) Cyr.. METHODS: The compounds were isolated through column chromatography and recrystallization. The structures were elucidated by means of physio-chemical data and spectroscopy. RESULT: Fourteen C-Glycosylflavones were isolated from this plant, and their structures were elucidated as apigenin (1) , vicenin (6,8-di-C-β-D-glucopyranosyl apigenin) (2),8-C-β-D-galactopyranosyl isovitexin(6-C-β-D-glucop yranosyl-8-C-β-D-galactopyranosyl apigenin) (3),6-C-β-D-galactopyranosyl vitexin ( 6-C-β-D-galactopyra nosyl-8-C-β-D-glucopyranosyl apigenin) (4), 6,8-di-C-α-L-arabinopyranosyl apigenin(5),schaftoside (6-C-β-D-glucopyranosyl-8-C-α-L-arabinosyl apigenin) (6), isoschaftoside (6-C-α-L -arabino syl-8-C-β-D-glucopyranosyl apigenin) (7), 6-C-β-D-galactopyranosyl-8-C-α-L-arabinosyl apigenin (8), 8-C-β-D-galactosyl apigenin (9 ) , vitexin (8-C-β-D-glucopyranosyl apigenin) (10), isovitexin (6-C-β-D-glucopyranosyl apigenin) (11) , tricetin 6,8-di-C-β-D-glucopyranosyl (12) , tricetin 6-C-α-L-arabinosyl-8-C-β-D-glucopyranosyl (13) and 7-O-β-D-glucopyranosy l-6-C-β-D-6″-acetyl-glucopyranosyl apigenin (14) .CONCLUSIONS:Compounds 3～8 and compounds 12 and 13 have been found in the plant for the first time, and c ompound 14 is a new C-glycosylflavone.