CAJ | 학술논문

目的探讨末梢全血CRP测定在儿童急性感染疾病中应用价值.方法 256例急性感染儿童治疗前分别测定末梢全血CRP、WBC计数值及抗生素治疗72 h后的末梢全血CRP、WBC计数值,以50例健康体检儿童为对照.结果细菌感染组CRP和WBC均明显升高,与正常对照组比较,t检验也有显著性差异(p<0.05);病毒感染组无显著性差异(p>0.05);细菌感染组198例患儿血CRP值增高,CRP阳性率88%,WBC测定阳性有95例,阳性率42 %,两者(2)/()检验有显著性差异(p<0.05);198例CRP增高的儿童进行抗生素治疗72 h后,末梢全血CRP明显下降,与治疗前相比,t检验也有显著性差异(p<0.05),WBC计数只有轻度下降,与治疗前相比,t检验无显著性差异(p>0.05).结论末梢全血CRP 的测定具有快速准确、灵敏度高、所用标本量少的特点,是诊断儿童急性感染疾病时区别细菌和病毒感染的重要指标,在临床上的用药及疗效观察上有重要的临床应用价值.
목적 탐토말소전혈CRP측정재인동급성감염질병중응용개치.방법 256례급성감염인동치료전분별측정말소전혈CRP、WBC계수치급항생소치료72 h후적말소전혈CRP、WBC계수치,이50례건강체검인동위대조.결과 세균감염조CRP화WBC균명현승고,여정상대조조비교,t검험야유현저성차이(p<0.05);병독감염조무현저성차이(p>0.05);세균감염조198례환인혈CRP치증고,CRP양성솔88%,WBC측정양성유95례,양성솔42 %,량자(2)/()검험유현저성차이(p<0.05);198례CRP증고적인동진행항생소치료72 h후,말소전혈CRP명현하강,여치료전상비,t검험야유현저성차이(p<0.05),WBC계수지유경도하강,여치료전상비,t검험무현저성차이(p>0.05).결론 말소전혈CRP 적측정구유쾌속준학、령민도고、소용표본량소적특점,시진단인동급성감염질병시구별세균화병독감염적중요지표,재림상상적용약급료효관찰상유중요적림상응용개치.
Objective To discuss the value of CRP detection by peripheral whole blood in diagnosis of children's acute infectious disease.Methods The level of CRP(serum and whole blood) and white blood cell(WBC)counts of 256 patients suffering from acute infections were detected before treatment and after antibiotic treatment for 72 h respectively, 50 children of normal health examination were selected as a control group Results The level of CRP and WBC in bacteria infection group increased significantly, compared with the normal control group (p<0.05),the level of CRP and WBC in viral infection group had no significant difference(p>0.05),the level of CRP in 198 cases of bacteria infection group was increased, the positive rate of CRP was 88%, the level of WBC in 95 cases was positive, the positive rate of 42%, whichever in χ2 test were significantly different(p<0.05).The level of CRP in 198 cases of children was obviously reduced 72 hours after treatment with antibiotics, showing difference(p<0.05),while WBC mild decline after treatment and no significant different (p>0.05).Conclusion The CRP detecting with peripheral blood, which characterized by rapid, accuracy, high sensitivity, and less specimen is an important indicator for the bacterial and viral infection of children's acute infectious disease.It has the clinical value in the drug-using and therapeutic observation.