湘潭大学自然科学学报
湘潭大學自然科學學報
상담대학자연과학학보
NATURAL SCIENCE JOURNAL OF XIANGTAN UNIVERSITY
2010年
3期
17-21
,共5页
图形表示%DNA序列%几何中心%波动幅度%相似度量%相似分析
圖形錶示%DNA序列%幾何中心%波動幅度%相似度量%相似分析
도형표시%DNA서렬%궤하중심%파동폭도%상사도량%상사분석
graphical representation%DNA sequence%geometrical center%fluctuation%similarity measure%similarity analysis
基于DNA序列的混沌游戏表示, 得到了一种新的能够避免信息损失的DNA序列的3维图形表示. 同时, 利用特征曲线的几何中心和波动幅度构造4维向量来刻画DNA序列. 基于两种新的相似度量, 对11种物种的β球蛋白基因序列进行相似性分析, 所得结果与生物学中的进化关系基本一致.而且通过比较分析,提出的方法对较长生物序列的相似分析更有效.
基于DNA序列的混沌遊戲錶示, 得到瞭一種新的能夠避免信息損失的DNA序列的3維圖形錶示. 同時, 利用特徵麯線的幾何中心和波動幅度構造4維嚮量來刻畫DNA序列. 基于兩種新的相似度量, 對11種物種的β毬蛋白基因序列進行相似性分析, 所得結果與生物學中的進化關繫基本一緻.而且通過比較分析,提齣的方法對較長生物序列的相似分析更有效.
기우DNA서렬적혼돈유희표시, 득도료일충신적능구피면신식손실적DNA서렬적3유도형표시. 동시, 이용특정곡선적궤하중심화파동폭도구조4유향량래각화DNA서렬. 기우량충신적상사도량, 대11충물충적β구단백기인서렬진행상사성분석, 소득결과여생물학중적진화관계기본일치.이차통과비교분석,제출적방법대교장생물서렬적상사분석경유효.
A 3D graphical representation of DNA sequence has been derived from chaos game representation of DNA sequence. The 3D graphical representation also avoids loss of information. The geometrical centers and fluctuation of characteristic curve have been grouped into a four-component vector to represent the DNA sequence. Two new efficient similarity/dissimilarity measure, Similarity Measure F and new Correlation Measure, are outlined. The examination of similarities based on less and simply-computed components among the full coding sequences of β-globin gene of 11 different species illustrates the utility, convenience and efficiency of the approach. Moreover, the examination of similarities among the full coding sequences of β-globin gene of different species shows our graphical representation method is more effective to the comparative study of long DNA sequences.
