国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2009年
23期
86-88
,共3页
粪肠球菌%屎肠球菌%耐药性
糞腸毬菌%屎腸毬菌%耐藥性
분장구균%시장구균%내약성
Enterococcus faecalis%Enterococcus faecium%Drug resistance
目的 分析常见肠球菌在临床标本中的分布及对常用抗菌药物的耐药性,为临床治疗提供参考.方法 采用法国梅里埃生物API鉴定系统进行菌种鉴定,并采用K-B纸片扩散法进行体外耐药监测及统计耐药率.结果 肠球菌的临床分离率为8.78%,分类以粪肠球菌为主,其次为屎肠球菌,肠球菌属对利福平、四环素、红霉素、达福普汀、氯霉素耐药率较高.而对万古霉素、替考拉宁和呋喃妥因仍然保持良好的敏感性.粪肠球菌对青霉素、氨苄西林、左旋氧氟沙星的耐药率分别为2.4%、2.4%、5.9%,均低于屎肠球菌的90.7%、88.9%、13.0%,屎肠球菌对四环索、氯霉素的耐药率分别为51.9%和48.1%,均低于粪肠球菌的95.3%和78.1%.结论 临床标本中,肠球菌在泌尿生殖道标本中的分布最高,粪肠球菌和屎肠球菌的耐药谱明显不同,在重症感染时可选用万古霉素、替考拉宁和呋喃妥因进行治疗.
目的 分析常見腸毬菌在臨床標本中的分佈及對常用抗菌藥物的耐藥性,為臨床治療提供參攷.方法 採用法國梅裏埃生物API鑒定繫統進行菌種鑒定,併採用K-B紙片擴散法進行體外耐藥鑑測及統計耐藥率.結果 腸毬菌的臨床分離率為8.78%,分類以糞腸毬菌為主,其次為屎腸毬菌,腸毬菌屬對利福平、四環素、紅黴素、達福普汀、氯黴素耐藥率較高.而對萬古黴素、替攷拉寧和呋喃妥因仍然保持良好的敏感性.糞腸毬菌對青黴素、氨芐西林、左鏇氧氟沙星的耐藥率分彆為2.4%、2.4%、5.9%,均低于屎腸毬菌的90.7%、88.9%、13.0%,屎腸毬菌對四環索、氯黴素的耐藥率分彆為51.9%和48.1%,均低于糞腸毬菌的95.3%和78.1%.結論 臨床標本中,腸毬菌在泌尿生殖道標本中的分佈最高,糞腸毬菌和屎腸毬菌的耐藥譜明顯不同,在重癥感染時可選用萬古黴素、替攷拉寧和呋喃妥因進行治療.
목적 분석상견장구균재림상표본중적분포급대상용항균약물적내약성,위림상치료제공삼고.방법 채용법국매리애생물API감정계통진행균충감정,병채용K-B지편확산법진행체외내약감측급통계내약솔.결과 장구균적림상분리솔위8.78%,분류이분장구균위주,기차위시장구균,장구균속대리복평、사배소、홍매소、체복보정、록매소내약솔교고.이대만고매소、체고랍저화부남타인잉연보지량호적민감성.분장구균대청매소、안변서림、좌선양불사성적내약솔분별위2.4%、2.4%、5.9%,균저우시장구균적90.7%、88.9%、13.0%,시장구균대사배색、록매소적내약솔분별위51.9%화48.1%,균저우분장구균적95.3%화78.1%.결론 림상표본중,장구균재비뇨생식도표본중적분포최고,분장구균화시장구균적내약보명현불동,재중증감염시가선용만고매소、체고랍저화부남타인진행치료.
Objective To investigate the distribution and resistance of common Enterococci isolated from clinical specimens in our hospital and to apply some suggestions for treating infections to the clinic.Methods The microbiological system API was used to identify bacteria and the drug-resistance in vitro was determined by K-B methods.Results The clinical isolation rate of enterococci was 8.78%. The main strain of enterococci was Enterococcus faecalis. Enterococcus faecium was the second one.The drug-resistance rate of Enterococci to Rifampin,Tetracycline,Erythromycin,Dalfopristin,Chloramphenicol was high.But it was still sensitive to Vancomycin,Teicoplanin,Nitrofurantoin.The resistance rate of Enterococcus faecalis to Penicillin,Ampicillin,Levofloxacin were2.4%,2.4% and 5.9% respectively .They were lower than Enterococcus faecium (90.7%, 88.9% and 13.0%); The resistance rate of Enterococcus faecium to tetracycline,chloramphenicol were 51.9%,48.1 %. Which were lower than the Enterococcus faecalis 95. 3%,78.1%.Conclusions The distribution rate of Enterococcus spp in genitourinary tract specimens is the highest.Resistance of Enterococcus faecalis and Enterococcus faecium is different.We should choose vanc.omycin,teicoplanin or Nitrofurantoin in severe infection.
