CAJ | 학술논문

目的探讨A型肉毒毒素治疗特发性眼睑痉挛及Meige综合征的疗效.方法采用A型肉毒毒素局部多点注射治疗特发性眼睑痉挛及Meige综合征32例,对治疗前后的病情随访并进行分级比较.结果症状完全缓解20例,占62.5%,明显缓解11例,占34.4%,部分缓解1例,占3.1%,疗效平均持续约3～6个月,复发者重复注射仍有效且剂量无增加,局部不良反应轻微、短暂.结论局部注射A型肉毒毒素治疗特发性眼睑痉挛及Meige综合征是一种安全有效且简便易行的方法,可重复注射.
목적 탐토A형육독독소치료특발성안검경련급Meige종합정적료효.방법 채용A형육독독소국부다점주사치료특발성안검경련급Meige종합정32례,대치료전후적병정수방병진행분급비교.결과 증상완전완해20례,점62.5%,명현완해11례,점34.4%,부분완해1례,점3.1%,료효평균지속약3～6개월,복발자중복주사잉유효차제량무증가,국부불량반응경미、단잠.결론 국부주사A형육독독소치료특발성안검경련급Meige종합정시일충안전유효차간편역행적방법,가중복주사.
Objective To explore the efficacy of botulinum toxin type A (BOTOX-A) for treatment of blepharospasm and Meige syndrome. Methods Local multi-point injection of BOTOX-A was performed for 32 patients of blepharospasm and Meige syndrome. The efficacy and side effects were compared between the results before and after injection. Results Symptoms of 62.5% of the patients were completely relieved,34.4% were obviously relieved,3.1% were partially relieved. The average of therapeutic efficacy lasted 3 to 6 monthes.It was effective to the recurrent patients repeated with injection.Local untoward effect was light and transient. Conclusions Local injection of BOTOX-A is a simple,effective and safe therapy for blepharospasm and Meige syndrome.