中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2012年
2期
105-107
,共3页
鼻咽肿瘤%磁共振弥散加权成像%表观弥散系数
鼻嚥腫瘤%磁共振瀰散加權成像%錶觀瀰散繫數
비인종류%자공진미산가권성상%표관미산계수
Nasopharyngeal neoplasm%Diffusion-weighted magnetic resonance imaging%Apparent diffusion coefficient
目的 探讨磁共振弥散加权成像(DWMRI)能否预测鼻咽癌调强放疗后复发和转移以及判断靶区范围的价值.方法 回顾2008年6月起初次调强放疗的鼻咽癌病历资料,选择有复发或转移36例和无复发转移36例作对照.对两组病例在DWMRI上测量其疗前肿瘤表观弥散系数(ADC值),并行成组t检验推测ADC值是否能预测鼻咽癌复发和转移.回顾分析局部区域复发病例放疗前MRI,从影像学角度分析DWMRI是否有助于判断靶区范围.结果 复发或转移组、对照组疗前ADC均值分别为(0.753 ±0.091)×10-3、(0.793±0.094) ×10-3mm2/s (t=-1.79,P=0.078).影像学回顾分析显示DWMRI在低本底上突显了肿瘤侵犯范围,局部区域复发共16例,15例疗前常规MRI弥散序列在病变范围上一致,1例复发患者DWMRI序列较常规序列更准确地预测了病变复发部位.结论 DWMRI结合常规MRI可更准确地判断鼻咽癌靶区范围,但其疗前ADC值的高低与鼻咽癌复发或转移并无关联.
目的 探討磁共振瀰散加權成像(DWMRI)能否預測鼻嚥癌調彊放療後複髮和轉移以及判斷靶區範圍的價值.方法 迴顧2008年6月起初次調彊放療的鼻嚥癌病歷資料,選擇有複髮或轉移36例和無複髮轉移36例作對照.對兩組病例在DWMRI上測量其療前腫瘤錶觀瀰散繫數(ADC值),併行成組t檢驗推測ADC值是否能預測鼻嚥癌複髮和轉移.迴顧分析跼部區域複髮病例放療前MRI,從影像學角度分析DWMRI是否有助于判斷靶區範圍.結果 複髮或轉移組、對照組療前ADC均值分彆為(0.753 ±0.091)×10-3、(0.793±0.094) ×10-3mm2/s (t=-1.79,P=0.078).影像學迴顧分析顯示DWMRI在低本底上突顯瞭腫瘤侵犯範圍,跼部區域複髮共16例,15例療前常規MRI瀰散序列在病變範圍上一緻,1例複髮患者DWMRI序列較常規序列更準確地預測瞭病變複髮部位.結論 DWMRI結閤常規MRI可更準確地判斷鼻嚥癌靶區範圍,但其療前ADC值的高低與鼻嚥癌複髮或轉移併無關聯.
목적 탐토자공진미산가권성상(DWMRI)능부예측비인암조강방료후복발화전이이급판단파구범위적개치.방법 회고2008년6월기초차조강방료적비인암병력자료,선택유복발혹전이36례화무복발전이36례작대조.대량조병례재DWMRI상측량기료전종류표관미산계수(ADC치),병행성조t검험추측ADC치시부능예측비인암복발화전이.회고분석국부구역복발병례방료전MRI,종영상학각도분석DWMRI시부유조우판단파구범위.결과 복발혹전이조、대조조료전ADC균치분별위(0.753 ±0.091)×10-3、(0.793±0.094) ×10-3mm2/s (t=-1.79,P=0.078).영상학회고분석현시DWMRI재저본저상돌현료종류침범범위,국부구역복발공16례,15례료전상규MRI미산서렬재병변범위상일치,1례복발환자DWMRI서렬교상규서렬경준학지예측료병변복발부위.결론 DWMRI결합상규MRI가경준학지판단비인암파구범위,단기료전ADC치적고저여비인암복발혹전이병무관련.
Objective To investigate the value of diffusion-weighted magnetic resonance imaging (DWMRI) in gross tumor volume definition and localregional recurrence/distant metastasis prediction in nasopharyngeal carcinoma ( NPC). Methods From Jun. 2008 to Feb. 2011, each of 36 patients with or without Iocalregional recurrence and/or distant metastasis treated by intensity-modulated radiotherapy in our hospital was matched in this study. The difference of apparent diffusion coefficient ( ADC) values between these two groups was compared by t-test method. The conventional MRI and DWMRI before treatment were centrally reviewed to evaluated whether DWMRI would benefit to the definition of gross tumor volume.Results The mean ADC value were (0. 753 ±0. 091) x 10 -3 mm2/s and (0. 793 ±0. 094) x10-3 mm2/s in treatment failure group and control group, respectively ( t = - 1. 79 ,P = 0. 078) . The extension of gross tumor volume were much more outstanding in DWMRI when compared to conventional MRI. DWMRI predicted localregional recurrence more accuracy than conventional MRI in one patient . Conclusions DWMRI is help to definition of gross tumor volume. The ADC value before radiotherapy can not predict the localregional recurrence and/or distant metastasis for nasopharyngeal carcinoma.
