CAJ | 학술논문

目的正规的认知功能评价结合脱氧葡萄糖正电子发射断层摄影术(FDG-PET)检查和影像学改变,分析非流利失语型额颞叶痴呆(FTD)患者的神经心理学特征.方法选择临床、影像、皮质葡萄糖代谢功能以及神经心理学评价均符合非流利失语型FTD患者,动态评价其神经语言学以及多种认知功能.按其特殊的神经心理学特点结合FDG-PET分析神经心理学改变的皮质基础.结果 5例患者的核心症状均为隐袭起病、慢性进行性的非流利型失语,伴随的突出改变为视空间、字词级阅读保留好,记忆相对好,以非语言记忆保留更突出.生活适应能力损害相对晚.患者均有相应的皮质糖代谢改变基础.结论非流利失语型FTD患者的视空间能力、字词级阅读能力以及生活适应能力损害晚,与相应的皮质代谢功能相关,可以帮助照料者有效指导、调整患者的适应能力训练.
목적 정규적인지공능평개결합탈양포도당정전자발사단층섭영술(FDG-PET)검사화영상학개변,분석비류리실어형액섭협치태(FTD)환자적신경심이학특정.방법 선택림상、영상、피질포도당대사공능이급신경심이학평개균부합비류리실어형FTD환자,동태평개기신경어언학이급다충인지공능.안기특수적신경심이학특점결합FDG-PET분석신경심이학개변적피질기출.결과 5례환자적핵심증상균위은습기병、만성진행성적비류리형실어,반수적돌출개변위시공간、자사급열독보류호,기억상대호,이비어언기억보류경돌출.생활괄응능력손해상대만.환자균유상응적피질당대사개변기출.결론 비류리실어형FTD환자적시공간능력、자사급열독능력이급생활괄응능력손해만,여상응적피질대사공능상관,가이방조조료자유효지도、조정환자적괄응능력훈련.
Objective To analyse the neuropsychological changing of nonfluent aphasia frontotemporal dementia (nf-FTD) with the FDG-PET, MRI and fMRI. Methods The language and other cognitive function were dynamically estimated by standard neuropsychological assessment which modified by Chinese. Compared with FDG-PET and fMRI, the relationship between the neuropsychologieal changing and the cortex function was studied. Results All the 5 patients met the criteria of nf-FTD by Association for Frontotemporal Dementias, with core syndrome and other supptted syndrome. And still they had the good word reading, calculation by pen, and the un-speechmemory. And they also had the related well living ability. They all had the related cortext metabolism support. Conclusions nf-FTD patients preserve the word reading, visuapacial ability and calculation by pen. These can help us to give the effective advise about the patients training and caring and to give them the chance to show their real social skill.