中华眼科杂志
中華眼科雜誌
중화안과잡지
Chinese Journal of Ophthalmology
2010年
1期
25-28
,共4页
葡萄膜炎%前%视觉%预后
葡萄膜炎%前%視覺%預後
포도막염%전%시각%예후
Uveitis%anterior%Vision%Prognosis
目的 探讨前葡萄膜炎的临床特点、治疗效果、视力预后及诊治中存在的问题.方法 回顾性系列病例研究.收集2001年1月至2007年6月期间在天津市眼科医院诊治的各类前葡萄膜炎患者478例,男性281例,女性197例;平均发病年龄(36±15)岁.通过详细临床检查、实验室检查和治疗观察,对其临床类型、疗效、并发症及视力预后进行分析.结果 急性前葡萄膜炎242例(50.6%),复发性前葡萄膜炎197例(41.2%),慢性前葡萄膜炎39例(8.2%).依据病因分为特发性前葡萄膜炎231例(48.3%),不伴有全身疾病的人类白细胞抗原-B27阳性葡萄膜炎76例(15.9%),病毒性葡萄膜炎52例(10.9%),合并强直性脊柱炎34例(7.1%),Fuchs综合征29例(6.1%),青光眼睫状体炎综合征24例(5.0%)及幼年性关节炎合并葡萄膜炎17例(3.6%).各种并发症发生率为31.6%(151例),轻度视力损害(低于0.5)发生率为11.1%(53例),中度和重度视力损害(低于0.3)为7.5%(36例),致肓率(低于0.05)为2.5%(12例).结论 前葡萄膜炎临床类型多样,特发性前葡萄膜炎、人类白细胞抗原-B27相关性前葡萄膜炎及病毒性前葡萄膜炎是常见类型,完善特异性实验室检查项目有助于病因诊断和给予适当治疗.
目的 探討前葡萄膜炎的臨床特點、治療效果、視力預後及診治中存在的問題.方法 迴顧性繫列病例研究.收集2001年1月至2007年6月期間在天津市眼科醫院診治的各類前葡萄膜炎患者478例,男性281例,女性197例;平均髮病年齡(36±15)歲.通過詳細臨床檢查、實驗室檢查和治療觀察,對其臨床類型、療效、併髮癥及視力預後進行分析.結果 急性前葡萄膜炎242例(50.6%),複髮性前葡萄膜炎197例(41.2%),慢性前葡萄膜炎39例(8.2%).依據病因分為特髮性前葡萄膜炎231例(48.3%),不伴有全身疾病的人類白細胞抗原-B27暘性葡萄膜炎76例(15.9%),病毒性葡萄膜炎52例(10.9%),閤併彊直性脊柱炎34例(7.1%),Fuchs綜閤徵29例(6.1%),青光眼睫狀體炎綜閤徵24例(5.0%)及幼年性關節炎閤併葡萄膜炎17例(3.6%).各種併髮癥髮生率為31.6%(151例),輕度視力損害(低于0.5)髮生率為11.1%(53例),中度和重度視力損害(低于0.3)為7.5%(36例),緻肓率(低于0.05)為2.5%(12例).結論 前葡萄膜炎臨床類型多樣,特髮性前葡萄膜炎、人類白細胞抗原-B27相關性前葡萄膜炎及病毒性前葡萄膜炎是常見類型,完善特異性實驗室檢查項目有助于病因診斷和給予適噹治療.
목적 탐토전포도막염적림상특점、치료효과、시력예후급진치중존재적문제.방법 회고성계렬병례연구.수집2001년1월지2007년6월기간재천진시안과의원진치적각류전포도막염환자478례,남성281례,녀성197례;평균발병년령(36±15)세.통과상세림상검사、실험실검사화치료관찰,대기림상류형、료효、병발증급시력예후진행분석.결과 급성전포도막염242례(50.6%),복발성전포도막염197례(41.2%),만성전포도막염39례(8.2%).의거병인분위특발성전포도막염231례(48.3%),불반유전신질병적인류백세포항원-B27양성포도막염76례(15.9%),병독성포도막염52례(10.9%),합병강직성척주염34례(7.1%),Fuchs종합정29례(6.1%),청광안첩상체염종합정24례(5.0%)급유년성관절염합병포도막염17례(3.6%).각충병발증발생솔위31.6%(151례),경도시력손해(저우0.5)발생솔위11.1%(53례),중도화중도시력손해(저우0.3)위7.5%(36례),치황솔(저우0.05)위2.5%(12례).결론 전포도막염림상류형다양,특발성전포도막염、인류백세포항원-B27상관성전포도막염급병독성전포도막염시상견류형,완선특이성실험실검사항목유조우병인진단화급여괄당치료.
Objective To explore the clinical characters, effects of treatment, the prognosis of visual acuity and the problems in the treatment of the anterior uveitis.Methods The retrospective case series study was used to observe the clinical characters and treatment effects of 478 cases of anterior uveitis from January 2001 to June 2007 in Tianjin Eye Hospital.Among the 478 cases of patients, the male was 281 cases and the female was 197 cases.The mean age was (36 ± 15)years old.Both the clinical examinations and immunologic investigations were performed.The clinical characters, effects of treatment, complications and prognosis of the anterior uveitis were analyzed.Results There were 242 cases (50.6% ) with acute anterior uveitis, 197 cases (41.2%) with recurrent anterior uveitis and 39 cases (8.2%) with chronic anterior uveitis.There were 231 cases(48.3%) with idiopathic uveitis, 76 cases (15.9%) with human leukocyte antigen-B27 associated uveitis without systemic diseases, 52 cases (10.9%) with herpetic uveitis, 34 cases (7.1% ) with ankylosing spondylitis, 29 cases (6.1% ) with Fuchs syndrome, 24 cases (5.0%) with glaucomatocyclitic crisis and 17 cases (3.6%) with juvenile idiopathic arthritis-associated uveitis.The rate of complications was 31.6% (151 cases) , the rate of mild visual impairment (less than 0.5) was 11.1% (53 cases) , the moderate and severe visual impairment (less than 0.3) was 7.5% (36 cases), and the rates of blindness (less than 0.05) was 2.5% (12 cases).Conclusions The types of anterior uveitis are varied.Idiopathic anterior uveitis, human leukocyte antigen-B27 associated uveitis and herpetic uveitis are the most common entities.The careful clinical and immunologic examinations could be benefit for the etiological diagnosis and prompt treatment
